LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

B.Sc. DEGREE EXAMINATION – PLANT BIOLOGY & PLANT BIO-TECH.

FIFTH SEMESTER – APRIL 2012

PB 5405 – MEDICAL MICROBIOLOGY

 

 

Date : 27-04-2012              Dept. No.                                        Max. : 100 Marks

Time : 1:00 – 4:00

 

 

Part – A

 

Answer all the following, each answer within 50 words:                                      (10 x 2 = 20 marks)

 

1. Distinguish between moist heat and dry heat sterilization.
2. Bring out the features of Koch postulates.
3. Give the significance of β-lactam ring.
4. Comment on phenol co-efficient test.
5. Write short notes on Gnotobiotics.
6. What are toxoids? Give example.
7. Write about the causative agents of Histoplasmosis.
8. Give salient features of HB vaccine.
9. Write about the causative agents of dermatophytoses.
10. Give the chemistry of tetanus toxins.

 

Part – B

 

Answer the following, each answer  within 500 words.  Draw diagrams wherever necessary:

         (5 x 7 = 35 marks)

 

11. (a) Give the contributions of Louis Pasteur and Edward Jenner.

Or

(b) List out the properties of chemicals agents that control microbial growth. Add notes

on alcohols.

 

12. (a) With illustrations, explain the mechanism of action of sulpha drugs.

Or

(b) Give the sources, mode of action and applications of streptomycin.

 

13. (a) Differentiate between the exo- and endo- toxins of human pathogens in the form of a tabular column.

Or

(b) Write notes on any 2 tests based on antigen-antibody reactions.

 

14. (a) Mention about pathogen, disease cycle and control measures of tuberculosis.

Or

(b) Write about pathogen, disease cycle and control measures of chicken pox.

 

15. (a) Describe about pathogen, disease cycle and control measures of syphilis.

Or

(b) Mention about pathogen, disease cycle and control measures of malaria.

 

 

 

 

Part – C

 

Answer Any THREE of the following, each within 1200 words, draw diagrams wherever necessary:                                                                                               (3 x 15 = 45 marks)

 

16. Write details on various physical agents that control microbial growth.
17. Describe various mechanisms of antibiotic resistance developed by the pathogens.
18. Explain various events of host – microbe interaction that takes place during disease development.

 

19. Write notes on pathogen, disease cycle, diagnoses and control measures of cholera.
20. Describe the pathogen, disease cycle, diagnoses and control measures of AIDS.

 

 

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