LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

M.Sc. DEGREE EXAMINATION – MEDICAL LAB. TECH.

HP 12

SECOND SEMESTER – APRIL 2007

ML 2809 – IMMUNOLOGY

 

 

 

Date & Time: 19/04/2007 / 1:00 – 4:00          Dept. No.                                                             Max. : 100 Marks

 

 

SECTION-A

 

Answer all the Questions:                             (10 x 2 = 20 Marks)

 

1. What is colonel selection theory?
2. Draw a neat labeled diagram of Class II MHC molecule.
3. What are Fab and Fc fragment?
4. Distinguish the attenuated from inactivated vaccines.
5. Expand the abbreviations: HAT, HGPRT, RIST.
6. What is drug induced haemolytic anemia?
7. Mention the glycoprotein present in the cell wall of the influenza virus.
8. What is antigenic drift and shift?
9. Write the principle involved in immunoelectrophoresis.
10. What is Digeorge’s syndrome?

 

SECTION-B

 

Answer any four of the following:             (4 x 10 = 40 Marks)

 

11. What is pinocytosis? Describe the innate immune mechanism.
12. Give an account on secondary lymphoid organs with suitable diagram.
13. Discuss briefly the types of precipitation reactions.
14. Mention the different types of vaccines? Explain recombinant vector vaccine preparation.
15. Describe the structure and the functions of MHC molecules.
16. Write short notes on Interferon and Tumor necrotic factor.

 

 SECTION-C

 

Answer any two of the following:                 ( 2 x 20 = 40 Marks)

 

17. Write an essay on different types of immunoglobulins with suitable diagrams.
18. Describe the Type I, II and III hypersensitivity reactions.
19. Give a detailed account on autoimmune diseases.
20. Write notes on: a) ELISA      b) RIA

 

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