LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
M.Sc. DEGREE EXAMINATION – MEDICAL LAB TECHNOLOGY
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SECOND SEMESTER – APRIL 2006
ML 2952 – ADVANCED LAB. TECHNIQUES
Date & Time : 24-04-2006/9.00-12.00 Dept. No. Max. : 100 Marks
Part A (Answer All) 10 ´ 2 = 20
- List out any four protein transfer procedure.
- What is ponceou S and PVDF?
- What are ramification amplification?
- Write the goals of HGP.
- Define gene therapy.
- Define obligatory paternal gene.
- What is direct exclusion?
- Define Two haplotype exclusion
- What is parentage testing?
- Expand the abbreviations: SWGDAM, FBI, CODIS, NDIS.
Part B (Answer any four) 4 ´ 10 = 40
- Write a short note on DNA polymorphism.
- Describe in brief human leukocyte antigen.
- Comment on documentation and reporting parentage-testing results.
- Describe in detail any two gene sequencing method.
- Give an account on human genome project.
- Describe in detail the micro array procedure and add a note on its clinical application.
Part C (Answer any two) 2 ´ 20 = 40
- Explain in detail the DNA testing method.
- Describe molecular techniques in the diagnosis of hematopoitic neoplasm.
- Write the importance of molecular techniques used in the diagnosis of leukemia.
- Discuss the techniques to detect antigen receptor gene rearrangement.
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