LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

      B.Sc. DEGREE EXAMINATION – PHYSICS & PL.BIO.& BIOTECH.

DE 8

FOURTH SEMESTER – APRIL 2008

AZ 4200 / 4202 – BIOINFORMATICS

 

 

 

Date : 24/04/2008                Dept. No.                                        Max. : 100 Marks

Time : 9:00 – 12:00

PART–A

Answer   ALL the  questions                                                                (10 x 2 =20)

1. What is computational biology?
2. State ‘FASTA FORMAT’
3. What is biological data mining?
4. Distinguish alpha helix from beta pleat.
5. Define Tanimoto coefficient.
6. How do you down load Rasmol?
7. What are logical operators? Mention any two of them.
8. Name various types of Amino acids found in the biosystem.
9. Comment on Phylip and SOPMA
10. Expand PUBMED and  EXPASY.

PART-B

Answer any FOUR  of the following                                                             (4X10=40)

1. Describe Sanger method of sequencing.
2. State the applications of human genome project.
3. When will you perform BLAST and CLUSTAL ‘W’? What would be the output?
4. Highlight the principle and application of microarray.
5. Demonstrate primary and secondary structure analysis of a protein using relevant tools
6. Write down a program in C to find the biggest of three numbers using logical operators.

PART-C

Answer any TWO of the following                                                    (2X20=40)

1. Propose a protocol for each of southern  blotting and DNA finger printing techniques.
2. Give an account on biological data bases and explain the tools associated for     analysis
3. Classify proteins based on structure.  How do you view them using bioinformatics tools.

20. Highlight the following in view of pharmainformatics: a) Target indentification and validation b)

Compound optimization   c) QSAR    d) Docking algorithm

 

 

Go To Main page

Latest Govt Job & Exam Updates:

View Full List ...