LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

B.Sc. DEGREE EXAMINATION – PLANT BIOLOGY & BIOTECHNOLOGY

AE 07

FIFTH SEMESTER – NOV 2006

PB 5401 – MEDICAL MICROBIOLOGY

(Also equivalent to PBB 401)

 

 

Date & Time : 03-11-2006/9.00-12.00         Dept. No.                                                       Max. : 100 Marks

 

 

Section-A     (20 marks)

Answer all questions

1. Choose the correct answer:            (5×1=5 marks)

 

1. Match A. Jenner B. Koch C. Widal D. Calmette with
2. Typhoid ii. Variola   iii. TB   iv. Cholera
3. A-i, B-iv,  C-iii,    D-I                        b. A-ii,   B-i,    C-iv,    D-iii
4. A-ii, B-iv,  C-i,      D-iii                      d. A-ii,   B-iii,  C-iv,    D-i
5. Statement A: Griseofulvin is obtained from penicillium.

Statement B:  It is an antibacterial antibiotic.

1. Statement A is correct, but Statement B is incorrect
2. Statement A is incorrect, but Statement B is correct
3. Both A and B are correct
4. Both A and B are incorrect
5. The most prominent resident flora of eye is :
6. Corynebacterium xerosis b. Vibrio cholera
7. Corynebacterium diphtheriae d. E.coli
8. Histoplasmoses is caused by a :
9. virus                  b. bacterium                c. actinomycete                       d. fungus
10. Quinine is associated with
11. rabies                b. syphilis                    c. malaria                                 d. tetanus

 

1. State whether True or False. (5×1=5 marks)

 

6. Sterilization involves the destruction of all forms of microbial life.
7. The term ‘chemotherapy’ was coined by Lister.
8. Intact skin is a good example of internal defense mechanism.
9. Chicken pox is caused by varicella zoster virus.
10. Tetanus is a communicable disease.

 

III. Complete the following :                                                                       (5×1=5 marks)

 

11. Application of _________ radiation to sterilize biological materials is called ______

stenlization.

12. ________ __________ tests are used to test the susceptibility of pathogens to drugs.
13. ______ of ________ refers to the route taken by pathogenic microbes to gain

entrance to hosts.

14. ________ _________ refers to fungal, infections which affect deeper systems of our

body.

15. Typhus fever is an example of ________ _______ disease.

 

 

1. Answer the following each within 50 words. (5×1=5 marks)

 

16. Enumerate any four characteristics of an ideal antimicrobial chemical agent.
17. Mention the source and mode of action of Nystatin.
18. What is relative immunity?
19. Write down any two symptoms of Hepatitis.
20. Name any two genera which cause dermatophytic infection in man.

 

Section-B

 

Answer any five questions, each within 350 words.                                (5×8=40 marks)

 

21. Compare the efficiency of moist heat and dry heat. Add a note on osmotic pressure

used  to control microbes.

22. Write about the mode of action of sulphonamides.
23. Discuss any one antigen-antibody reaction along with its applications.
24. Explain the morphological, cultural, physiological and antigenic characters of Mycobacterium tuberculosis.
25. Write about the disease cycle of malaria.
26. Expand the following with a footnote each :
27. Eto        ii. PABA         iii. TPCF          iv. DPT
28. Distinguish between :
29. Bactericidal and Bacteriostatic agent
30. Penicillin and Streptomycin (source)

iii. Endemic and Pandemic disease

1. Tetanus and Rabies (causal organism)
2. Define the following :
3. Fumigation       ii. Chemotherapy         iii. Transient Flora       iv. Amoebiasis

 

Section-C

 

Answer the following, each within 1500 words only.                           (2×20=40 marks)

 

29. a. Give an account of control of microbes by dry heat, radiation, phenols and heavy

metals.

or

1. Discus the causal organism, symptoms, treatment and control of cholera.
2. a. Compare and contrast Syphilis and Gonorrhoea..

or

1. Write short notes on
2. Gaseous chemosterilizers                   ii. Properties of Antibiotics

iii. Endotoxin                                          iv. Dermatophytoses

 

 

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