LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

M.Sc. DEGREE EXAMINATION – MEDICAL LAB TECHNOLOGY

HZ 02

SECOND SEMESTER – APRIL 2006

                                                                ML 2809 – IMMUNOLOGY

 

 

Date & Time : 21-04-2006/9.00-12.00         Dept. No.                                                       Max. : 100 Marks

 

 

Part A                                     (Answer All)                           10 X 2 = 20

 

1. What is HLA?
2. Explain clonal selection theory.
3. Define the term “apoptosis”
4. Comment on antigen presenting cell.
5. Draw the structure of IgA.
6. What is chemotactic reaction?
7. Write the functions of CD₄ and CD_8.
8. Explain the term “sensitization”.
9. Write the principle of pregnancy test.
10. List out the salient features of IL-1and IL-2.

 

Part B                                     (Answer any four)                  4 X 10 = 40

11.  What is immunity ?Give an account of innative immunity with suitable examples.

12. Describe in detail the structure and functions of secondary lymphoid organs.

13   Define cytokines.Write briefly various applications and types of interleukines.

14. Discuss any two precipitation reaction.
15. Write the mechanism of immunity against the viral infection.
16. Give a detailed account of MHC molecules.

 

Part C                                     (Answer any two)                              2 X 20 = 40

17. Discribe in detail the alternative and classical pathways of complement system.
18. Write an essay on different types of vaccines and add a note on immunization schedule.
19. Define hypersensitivity. Explain IgE mediated hypersensitivity reaction.
20. Write a note on the principle and significance of immunoelectrophoresis and ELISA.

 

 

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