LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
M.Sc. DEGREE EXAMINATION – MEDICAL LAB. TECH.
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SECOND SEMESTER – APRIL 2008
ML 2801 – HUMAN PATHOAGENS
Date : 17/04/2008 Dept. No. Max. : 100 Marks
Time : 1:00 – 4:00
PART A (Answer All) 10 ´ 2 = 20
- Write four examples of continuous cell lines.
- Differentiate pasteurization from flash pasteurization.
- Define plague and bacteriophage.
- Define quellung reaction.
- Define two methods of virus cultivation.
- Expand the abbreviations: PCR, LCR, LJ and RFLP.
- Differentiate autopsy from biopsy.
- Differentiate endotoxins from exotoxins.
- Define babes ernst granules and cuneiform arrangement.
- List four clinical syndromes caused by Salmonella in human beings.
PART B (Answer any four) 4 ´ 10 = 40
- Briefly describe the life cycle and laboratory diagnosis of Ascaris lumbricoides.
- Briefly describe the life cycle and pathogenesis of Entamoeba histolytica.
- Write a short note on clinical importance and life cycle of Trypanosoma brucei.
- Briefly discuss the life cycle and pathogenesis of pathogen causing malaria
- Discuss the principle, procedure, clinical significance and grading for Ziehl Neelsen staining.
- Comment on morphology and life cycle of Wuchereria bancrofti.
PART C (Answer any two) 2 ´ 20 = 40
- What is culture medium? Give an account on types of culture media.
- What is bacteriophage? Explain the lytic and lysogenic cycles in bacteriophage.
- What is a virus? Describe in detail the classification of viruses.
- Give an detailed account on life cycle and pathogenesis of Strongyloides stercoralis and Trichomonas vaginalis.
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