LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
M.Sc. DEGREE EXAMINATION – MEDICAL LAB. TECHNOLOGY
SECOND SEMESTER – APRIL 2011
ML 2811 – IMMUNOLOGY
Date : 05-04-2011 Dept. No. Max. : 100 Marks
Time : 1:00 – 4:00
Section A
Answer ALL the questions (2×10 = 20 Marks)
- What are acute phase proteins? Give one example.
- Differentiate active from passive acquired immunity.
- Mention the essential factors for antigenicity.
- Give the functions of MHC.
- How can graft rejection be prevented?
- Define affinity.
- What is the causative factor of Chediak – Higasi disease.
- What are Kupfer cells?
- List the cells of lymphoid and myeloid lineage.
- What is myasthenia gravis?
Section B
Answer any FOUR of the following (10×4 = 40 Marks)
- Explain the immunological functions of spleen.
- Write notes on the structure and biological properties of IgD and IgM.
- Give an account on the production of monoclonal antibodies.
- Enumerate immune response to tumours.
- Explain Rheumatoid arthiritis
- Name the different antigen antibody interactions? Explain Immunofluorescence.
Section C
Answer any TWO of the following (20×2 = 40 Marks)
- Explain the process of B cell differentiation. Add a note on cell surface markers.
- Discuss complement activation pathways.
- Write in detail on the causative factors, mechanism and symptoms of anaphylaxis.
- Tabulate the vaccination schedule in children and adults.
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