LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

M.Sc. DEGREE EXAMINATION – MEDICAL LAB TECHNOLOGY

HZ 5

SECOND SEMESTER – APRIL 2006

                                               ML 2952 – ADVANCED LAB. TECHNIQUES

 

 

Date & Time : 24-04-2006/9.00-12.00         Dept. No.                                                       Max. : 100 Marks

 

 

Part A                                     (Answer All)                          10 ´ 2 = 20

1. List out any four protein transfer procedure.
2. What is ponceou S and PVDF?
3. What are ramification amplification?
4. Write the goals of HGP.
5. Define gene therapy.
6. Define obligatory paternal gene.
7. What is direct exclusion?
8. Define Two haplotype exclusion
9. What is parentage testing?
10. Expand the abbreviations: SWGDAM, FBI, CODIS, NDIS.

Part B                                     (Answer any four)                 4 ´ 10 = 40

11. Write a short note on DNA polymorphism.
12. Describe in brief human leukocyte antigen.
13. Comment on documentation and reporting parentage-testing results.
14. Describe in detail any two gene sequencing method.
15. Give an account on human genome project.
16. Describe in detail the micro array procedure and add a note on its clinical application.

 

Part C                                     (Answer any two)                              2 ´ 20 = 40

17. Explain in detail the DNA testing method.
18. Describe molecular techniques in the diagnosis of hematopoitic neoplasm.
19. Write the importance of molecular techniques used in the diagnosis of leukemia.
20. Discuss the techniques to detect antigen receptor gene rearrangement.

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