LOYOLA COLLEGE (AUTONOMOUS), CHENNAI– 600 034
M.Sc. DEGREE EXAMINATION -medical laboratory technology
FIRST SEMESTER – NOVEMBER 2003
ML 1801 clinical BIOCHEMISTRY
06.11.2003 Max: 100 Marks
1.00 – 4.00
SECTION – A
Answer the following in ONE or TWO sentence (10 ´ 2 = 20 Marks)
- Differentiate glycogenolysis, from gluconeogenesis.
- Urea and Uric acid are the end products of __________.
- What is tetany and Gout?
- What is dysyuris and anuria?
- What are the isoenzymes of C.P.K name them and where is it found?
- What is the difference between a colorimeter and spectrophoto meter?
- Name the hormones which regulate blood sugar.
- What is the level of urea and creatinine in renal, prerenal and post renal conditions?
- Name and water soluble and FGT soluble vitamins with their function.
- Expand ACTH, PTH, S.G.O.T & S.G.P.T.
SECTION – B
Answer any four of the following (4 ´ 10 = 40 Marks)
- What is the importance of Alkaline phosphatase? What are the isoemzymes
of alkaline phosphatase? Give a brief account of their physiological role.
- Give in tabular form the levels of calcium, phosphorous alkaline phosphatase
and urinary calcium in any ten forms of disease.
- List the liver function test in case of obstructive, hepatocellular and transfusion reactions.
- What is toxiocology? Give any five substances with their dosage and effects in tabular form.
- What are electrolytes? State their importance.
- What is glycosylated haemoglobin? What is its importance in diabetes?
SECTION – C
Answer any TWO of the following (2 ´ 20 = 40 Marks)
- What are the cardiac enzymes? Name them in order and describe.
- Describe a colorimeter diagramatically, name the parts and give the corresponding filters used and how does it differ from spectrophotometer diagramatically.
- What is amylase and acid phosphatse? Give in detail their mode of action and implications.
- What is lipid profile? Give the lipid classification by fredrickson and explain the conditions.