LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
B.Sc. DEGREE EXAMINATION – PLANT BIOLOGY & PLANT BIO-TECH.
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FIFTH SEMESTER – April 2009
PB 5405 / PB 5401 – MEDICAL MICROBIOLOGY
Date & Time: 28/04/2009 / 1:00 – 4:00 Dept. No. Max. : 100 Marks
PART A (20 marks)
Answer All questions
I Choose the Correct Answer (5 x 1 = 5 marks)
- Match A) Jenner B) Metchnikoff C) Ehrlich D) Twort with i) Phagocytosis
- ii) Vaccination iii) Phage iv) Chemotheraphy
- a) A-ii, B-i, C-iv, D) iii b) A-ii, B-i, C-iii, D) iv
- c) A-ii, B-iv, C-i, D) iii d) A-ii, B-iii, C-iv, D) i
- Statement A: Sulfonamides are semisynthetic drugs.
Statement B: Mode of action is competitive inhibition.
- Statement Ais correct, but B is incorrect
- Statement A is incorrect, but B is correct
- Both A and B are correct
- d) Both A and B are incorrect
- Which of the following is a prominent resistant flora of vagina?
- E. coli b. Staphylococcus c. Lactobacillus d. Salmonella
- The causal organism of chicken pox is a:
- Fungus b. Protozoan c. Bacterium d. Virus
- The vector for malarial parasite is:
- Male Anopheles b. Female Anopheles c. Male Qulex d. Female Qulex
II State whether the following statements are True or False. (5 x 1 = 5 marks)
- Autoclave is used in dry heat sterilization.
- Nystatin is an antifungal antibiotic.
- Agglutination is the most striking of all test tube antigen-antibody reactions.
- Histoplasmosis is an example for systemic fungal infection.
- Typhus fever is a vector borne disease caused by Rickettsia.
III. Complete the following (5 x 1 = 5 marks)
- Application of silver nitrate to the eyes of newborn to control ophthalmic ____________
is called Credes method.
- ___________ acremonium is the source for the antibiotic cephalosporin.
- Transmission of disease is otherwise known as _______________.
- Rice water stool is the most prominent symptom of _______________.
- Hydrophobia is associated with the disease _______________.
- Answer the following, each in about 50 words (5 x 1 = 5 marks)
- What is fumigation?
- Mention any two features of chemotherapeutic agents.
- Enumerate any two points about external defense mechanisms.
- Write down any two morphological characteristics of Mycobacterium.
- Name any two genera of dermatophytic fungi.
PART B (5 x 8 = 40 marks)
Answer any five, each within 350 words only. Draw diagrams and flowcharts wherever necessary.
- Enumerate the characteristics of an ideal antimicrobial chemical agent. Add a note an
phenol .
- Write about the salient aspects of antibiotic sensitivity tests.
- Distinguish between exotoxins and endotoxins in tabular form.
- Discuss the causal organism, symptoms and control of chicken pox.
- Bring out the differences between Syphilis and Gonorrhea based on causal organism,
symptoms and incubation period.
- Expand the following with a foot note each:
- a) HTST b) MIC c) NMF d) HBV
- Define the following:
- a) Lockjaw b) Cold sterilization c) Chemotherapy d) Inflammation
- Write about the following:
- Symptoms and treatment of amoebiasis
- Causal organism of Tetanus
- Acids and alkalies as chemical agent of control
- Grieseofulvin
PART C (2 x 20 = 40 marks)
Answer the following, each within 1500 words only. Draw diagrams and flowcharts wherever necessary.
- a) Given an account on control of microbes by physical agents
(or)
- b) Give an outline of immunity. Add a note on blood as internal defense mechanism.
- a) Discuss the structure of HIV. Write about the symptoms, treatment and control of AIDS
(or)
- b) Describe in detail the causal organisms, symptom, lab diagnosis and prevention of
Cholera.
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