LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

M.Sc. DEGREE EXAMINATION – MEDICAL LAB. TECHNOLOGY

SECOND SEMESTER – APRIL 2012

ML 2811 – IMMUNOLOGY

 

 

Date : 19-04-2012             Dept. No.                                        Max. : 100 Marks

Time : 9:00 – 12:00

 

Section A

 

Answer ALL the Questions:                                                                                           (10 ×2 = 20 Marks)

 

1. Categorize the cells of immune system.
2. What is immunological memory?
3. Write any four properties of an antigen.
4. Define cross reactivity.
5. What are haptens?
6. What is immune tolerance?
7. What is Crohn’s disease?
8. Mention the symptoms of multiple sclerosis.
9. Define avidity.
10. What is antibody cross reativity?

 

 

SECTION B

 

Answer any FOUR of the following:                                                                                           (4 ×10 = 40 Marks)

 

11. Write notes on granulocytes.
12. What are the two types of adaptive immunity? Explain.
13. How are monoclonal antibodies produced? Explain
14. Explain the category of hypersensitivity that best describes haemolytic disease of the newborn.
15. Elaborate immunological aspects of DiGeorge syndrome.
16. Describe the purpose and technique of immunodiffusion.

 

SECTION C

 

Answer any TWO of the following:                                                                         (2 ×20= 40 Marks)

 

17. Write short notes on a) Bone marrow b) Thymus c) Spleen d) Lymph node.
18. Explain classical and alternative pathways of the complement system with suitable diagram.
19. Tabulate the vaccination schedule in children.
20. Discuss different types of ELISA.

 

 

 

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