LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

M.Sc. DEGREE EXAMINATION – ZOOLOGY

TS 23

SECOND SEMESTER – APRIL 2006

                                             ZO 2808 – CELL AND MOLECULAR BIOLOGY

 

 

Date & Time : 19-04-2006/FORENOON     Dept. No.                                                       Max. : 100 Marks

 

 

Part A                                               (Answer All)                                       10 ´ 2 = 20

 

1. Distinguish totipotent from pleuripotent stem cells.
2. How does ER synthesis lecithin?
3. Illustrate fluorescent activated cell sorted.
4. Define mDNA and add its significance.
5. Sketch avian flu H₅N₁
6. Differentiate error free and error prone system of repair.
7. Explain gestational diabetes.
8. What is genetic enhancement?
9. Comment on attenuation?
10. What is De Novo initiation?

Part B                                          (Answer any four)                                   4 ´ 10 = 40

11. How does golgi transport cargo vesicles to lysosome? Illustrate.
12. Illustrate Na⁺ – K⁺ pump being operated across the plasma membrane..
13. State the theories on carcinogenesis.
14. Describe the methods of finger printing.
15. Give an account of ionizing radiations and its characteristics
16. Explain oncogenes and growth factors. Add notes on nuclear oncogenes.

 

Part C                                           (Answer any two)                                   2 ´ 20 = 40

17. Explain the principle, protocol and application of FISH technique.
18. How are chromosomes studied? Propose a protocol. Discuss the role of giant

chromosomes and their significance.

19. Write an essay on DNA repair mechanism.
20. Give an account of Lac Operon of E. coli and positive control.

 

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LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

M.Sc. DEGREE EXAMINATION – ZOOLOGY

TS 29

SECOND SEMESTER – APRIL 2007

ZO 2808 – CELL AND MOLECULAR BIOLOGY

 

 

 

Date & Time: 17/04/2007 / 1:00 – 4:00         Dept. No.                                                       Max. : 100 Marks

 

 

 

SECTION – A

 

Answer ALL questions                                                                      (10 X 2 = 20 Marks)

 

1.Comment on Anaplasia.

2.Differentiate prophage and temporal phage.

3.What is nuclear genome?

4.Comment on oncogene activation.

5.Differentiate prokaryotic and eukaryotic cells.

6.Comment on polytene chromosome.

7.What are endocytosis and exocytosis?

8.Define Euphenics.

9.What is noval gene?

10.List out the significance of meiosis.

 

 

SECTION – B

 

Answer any FOUR questions                                                            (4 X 10 = 40 Marks)

 

11.Define transformation. Explain Griffith’s experiment in relation to transformation.

12.Explain the relationship between Telomere and aging process.

13.Explain the cytoplasmic influence of nucleus, inhibition of nucleus, influence of

nuclear maturation and chromosomal elimination.

14.Write notes on significance of museum specimen.

15.Define finger printing. Explain about making DNA finger printing.

16.Write an account on pedigree analysis.

 

SECTION – C

 

Answer any TWO questions                                                  (2 X 20 = 40 Marks)

 

17.Explain different functions of Lysosomes.

18.Define DNA replication. Explain the mechanism and different types of DNA

replication.

19.Write an essay on cancer as a genetic disease and write notes on oncogenes.

20.Give an account on Lac operon in E.coli.

 

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LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

M.Sc. DEGREE EXAMINATION – ZOOLOGY

DE 23

SECOND SEMESTER – APRIL 2008

ZO 2808 – CELL AND MOLECULAR BIOLOGY

 

 

 

Date : 17/04/2008            Dept. No.                                        Max. : 100 Marks

Time : 1:00 – 4:00

PART A                                (Answer all)                                        10 x 2 = 20 Marks

1. Comment on pachytene
2. What is cystic fibrosis?
3. What are oncogenes?
4. Explain the process of apoptosis
5. Write notes on sodium pump
6. Comment on Southern blot
7. What are kappa particles?
8. Mention the significance of eugenics
9. What is heterophagy?
10. Comment on radiation syndrome

PART B                                ( Answer any four)                                4 x 10 = 40 Marks

1. Explain the process staining and banding of chromosome
2. Write the various theories of carcinogens.
3. Give an account of genetics of aging
4. Write notes on deficiency and duplication of chromosomes
5. Describe the different organelles involved in the process of protein synthesis
6. Describe the characteristics of triplet codon

PART C                                 (Answer any two)                                    2 x 20 = 40 Marks

1. Write an essay on specific chromosome translocations, tumor suppressor genes and hereditary cancers
2. Give an account on trp operon hypothesis
3. Explain about human genome project
4. Write a detailed account on DNA from museum specimen

 

 

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LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

M.Sc. DEGREE EXAMINATION – ZOOLOGY

SECOND SEMESTER – APRIL 2011

ZO 2814 / 2808 – CELL AND MOLECULAR BIOLOGY

 

 

 

Date : 02-04-2011             Dept. No.                                        Max. : 100 Marks

Time : 1:00 – 4:00

 

PART – A

 

Answer all                                      (10×2 = 20 marks)

1. Differentiate malignant and benign tumour.
2. What is radiation genetics?
3. Comment on cystic fibrosis.
4. What is the primary function of ribosome?
5. Comment on southern blot.
6. Define replicon.
7. What is a genetic disorder?
8. Comment on telomeres.
9. What are the types of oncoproteins?
10. Comment on non-permissive cells.

PART – B

 

Answer any four                                 (4×10 = 40 marks)

 

11. Write notes on the effects of radiation in DNA.
12. Explain the role of ribosomes and peroxisomes.
13. Give an account on karyotyping.
14. Write notes on biogenesis of mitochondria and mitochondrial DNA.
15. What are the properties of genetic code? Explain.
16. Give an account of methods of gene sequencing.

 

PART – C

 

Answer any two                                  (2×10 = 40 marks)

 

17. Write an essay on tumour suppressor genes.
18. Differentiate prokaryotic and eukaryotic cell organization.
19. Give an account of DNA finger printing technology.
20. Explain the genetics of ageing process.

 

 

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LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

M.Sc. DEGREE EXAMINATION – ZOOLOGY

SECOND SEMESTER – APRIL 2012

ZO 2814 – CELL AND MOLECULAR BIOLOGY

 

 

Date : 17-04-2012             Dept. No.                                        Max. : 100 Marks

Time : 9:00 – 12:00

 

                    Part A                

       Answer ALL the questions:                                                                                            (10×2=20 Marks)

1. Define sedimentation coefficient.
2. What are tumour suppressor genes?
3. Comment on proto lysosomes.
4. Explain S-phase of cell cycle.
5. Write notes on metastasis.
6. What are carcinogens?
7. Differentiate heterochromatin from euchromatin.
8. What is selective permeable plasma membrane?
9. Define genomics.
10. Comment on puffing and gene expression.

 

Part B

Answer any FOUR questions:                                                                                      (4×10=40 Marks)

11. Explain the inherited disorders in man.
12. Give an account on mitosis.
13. Write notes on characters of cancer cells.
14. Explain transduction.
15. Discuss carcinogens and specific cancer.
16. Write an account on genetics of aging.

 

           Part C

Answer any TWO questions:                                                                                        (2×20=40 Marks)

 

17. Explain prokaryotic and eukaryotic organization.
18. Give an account on pedigree analysis.
19. Write an essay on Lac operon.
20. Explain tumour suppressor genes, inherited cancer genes and cellular function of oncoproteins.

 

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