Loyola College Question Paper 2006

Loyola College M.Sc. Medical Lab Technology April 2006 Medical Transcription Question Paper PDF Download

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             LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

M.Sc. DEGREE EXAMINATION – MEDICAL LAB TECHNOLOGY

HZ 7

FOURTH SEMESTER – APRIL 2006

                                                   ML 4900 – MEDICAL TRANSCRIPTION

 

 

Date & Time : 25-04-2006/9.00-12.00         Dept. No.                                                       Max. : 100 Marks

Part A                                     (Answer All)                          10 ´ 2 = 20

  1. Define two types of respiration.
  2. What are autoimmune diseases?
  3. What is fibrinolytics?
  4. Define Otitis media and Otitis externa.
  5. What are abbreviations in MT? Give two examples.
  6. Define aminocentesis.
  7. Define epilepsy and multiple sclerosis.
  8. What is a Transquilizer?
  9. Define diabetic retinopathy and glaucoma.
  10. Define cryosurgery and seizure disorder.

 

Part B                                     (Answer any four)                 4 ´ 10 = 40

  1. Describe two types of immunity in human body.
  2. Describe the transcription guidelines for: a) Abbreviations, b) Periods, c) Plurals and d) Acronyms.
  3. Describe the pathology of food in the gastrointestinal tract with a neat diagram.
  4. Write a short note on any three accessory organs of the skin in integumentary system.
  5. How will you transcribe voice message in medical transcription?
  6. Write a short note on functions of central nervous system and peripheral nervous system.

 

Part C                                     (Answer any two)                              2 ´ 20 = 40

  1. Draw a neat-labeled sketch of various parts of human eye. Add a note on any five of the lab procedure involved in ophthalmology.
  2. Explain the importance of parts of speech in MT.
  3. Write a note on pathology of pulmonary system with a neat diagram.
  4. Describe the laboratory procedure and pharmacological drugs involved in gynecology.

 

 

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Loyola College M.Sc. Medical Lab Technology April 2006 Immunology Question Paper PDF Download

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             LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

M.Sc. DEGREE EXAMINATION – MEDICAL LAB TECHNOLOGY

HZ 02

SECOND SEMESTER – APRIL 2006

                                                                ML 2809 – IMMUNOLOGY

 

 

Date & Time : 21-04-2006/9.00-12.00         Dept. No.                                                       Max. : 100 Marks

 

 

Part A                                     (Answer All)                           10 X 2 = 20

 

  1. What is HLA?
  2. Explain clonal selection theory.
  3. Define the term “apoptosis”
  4. Comment on antigen presenting cell.
  5. Draw the structure of IgA.
  6. What is chemotactic reaction?
  7. Write the functions of CD4 and CD8.
  8. Explain the term “sensitization”.
  9. Write the principle of pregnancy test.
  10. List out the salient features of IL-1and IL-2.

 

Part B                                     (Answer any four)                  4 X 10 = 40

11.  What is immunity ?Give an account of innative immunity with suitable examples.

  1. Describe in detail the structure and functions of secondary lymphoid organs.

13   Define cytokines.Write briefly various applications and types of interleukines.

  1. Discuss any two precipitation reaction.
  2. Write the mechanism of immunity against the viral infection.
  3. Give a detailed account of MHC molecules.

 

Part C                                     (Answer any two)                              2 X 20 = 40

  1. Discribe in detail the alternative and classical pathways of complement system.
  2. Write an essay on different types of vaccines and add a note on immunization schedule.
  3. Define hypersensitivity. Explain IgE mediated hypersensitivity reaction.
  4. Write a note on the principle and significance of immunoelectrophoresis and ELISA.

 

 

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Loyola College M.Sc. Medical Lab Technology April 2006 Human Pathogens Question Paper PDF Download

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             LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

M.Sc. DEGREE EXAMINATION – MEDICAL LAB TECHNOLOGY

HZ 1

SECOND SEMESTER – APRIL 2006

                                                         ML 2801 – HUMAN PATHOGENS

 

 

Date & Time : 19-04-2006/FORENOON     Dept. No.                                                       Max. : 100 Marks

Part A                                               (Answer All)                                       10 ´ 2 = 20

  1. What are the general characteristics of spirochaetes and compare those characteristics with other bacteria.
  2. List the virulent factors of Staphylococcus aureus.
  3. Give two examples of primary cell culture and continuous culture.
  4. What are virions?
  5. Give the causative agents of coccidioidiomycosis, Blastomycosis
  6. What are dimatiaceous fungi?
  7. Differentiate amoebic and bacillary dysentery.
  8. What are the characteristics of a fertilized egg of Ascaris
  9. Mention any four DNA viruses
  10. Write the mode of infection, portal of entry, infecting agent and site of localization of Fasciolopsis buski.

 

Part B                                          (Answer any four)                                   4 ´ 10 = 40

 

  1. Explain the circumstances and events leading to gas gangrene.
  2. Explain the action of Vibrio toxin and its pathogenesis.
  3. Discuss the four stages of disease caused by Rabies virus in humans.
  4. Enumerate the fungi causing chromomycosis. Add a note on its pathogenesis and clinical findings.
  5. Give a general account of intestinal flagellates.
  6. Write in detail about the life cycle of Ancylostoma duodenale.

 

Part C                                           (Answer any two)                                   2 ´ 20 = 40

  1. Write an essay on the four major clinical syndromes of Salmonella.
  2. Explain the two types of life cycle exhibited by phages.
  3. Give a general account of Candida albicans.
  4. Explain in detail the life cycle of malarial parasite in man.

 

 

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Loyola College M.Sc. Medical Lab Technology April 2006 Human Disorder Question Paper PDF Download

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             LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

M.Sc. DEGREE EXAMINATION – MEDICAL LAB TECHNOLOGY

HZ 8

FOURTH SEMESTER – APRIL 2006

                                                           ML 4950 – HUMAN DISORDER

 

 

Date & Time : 22-04-2006/9.00-12.00         Dept. No.                                                       Max. : 100 Marks

 

 

Part A                                     (Answer All)                          10 X 2 = 20

 

  1. What is gaucher’s disease?
  2. Write the importance of tyrosine.
  3. Comment on congenital heart disease.
  4. Differentiate acute and chronic ischaemia.
  5. List out the causes of diarrhea.
  6. Define gastritis.
  7. What is IOP ?
  8. What is prostate specific antigen?.
  9. Explain secretory otitis media.
  10. Write critical notes on conn’s syndrome.

 

Part B                                     (Answer any four)                 4 X 10 = 40

  1. Give an account of glycogen storage diseases.
  2. What is angina pectoris? Explain their types.
  3. Write a short notes on cataract and glaucoma.
  4. Describe in detail the characteristics of peptic ulcer.
  5. Explain different types of hepatitis.
  6. Give an account of phenylketonuria and alkaptonuria with their reactions.

 

Part C                                     (Answer any two)                              2 X 20 = 40

  1. Write an essay on effects of hypertension on human body.
  2. Give a detailed account on the features of stomach and colon cancers
  3. Describe in detail the structure and abnormalities of Adrenal gland
  4. Describe in detail the diseases related human ear.

 

 

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Loyola College M.Sc. Medical Lab Technology April 2006 Human Anatomy & Physiology Question Paper PDF Download

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             LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

M.Sc. DEGREE EXAMINATION – MEDICAL SOCIOLOGY

HZ 3

SECOND SEMESTER – APRIL 2006

                                            ML 2901 – HUMAN ANATOMY & PHYSIOLOGY

 

 

Date & Time : 28-04-2006/9.00-12.00         Dept. No.                                                       Max. : 100 Marks

 

 

Part A                                     (Answer All)                          10 ´ 2 = 20

  1. What are the different layers of human skin?
  2. Name the two types of sweat glands.
  3. What are gigantism and dwarfism?
  4. Define tidal volume and inspiratory reserve volume.
  5. What is cardiac cycle?
  6. Classify broadly the nervous system.
  7. Write the classification of muscles.
  8. What are the hormones secreted by the posterior lobes of pituitary gland.
  9. What are the secondary sexual organs in male?
  10. What is amniocentesis?

Part B                                     (Answer any four)                 4 ´ 10 = 40

  1. Give an account on gastric function test.
  2. Define autonomic nervous system. Write the differences between parasympathetic

and sympathetic nervous system.

  1. Give an account on respiratory organs.
  2. Explain the structure and functions of kidney.
  3. Give an account on the pancreatic hormones.
  4. Describe various methods of birth control.

 

Part C                                     (Answer any two)                              2 ´ 20 = 40

  1. Give an account on functions of various parts of central nervous system.
  2. Explain in detail the role of growth hormone and associated disorders.
  3. What is menstrual cycle? Explain the three phases involved in it.
  4. Give a detailed account on the hydrolytic enzymes in man.

 

 

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Loyola College M.Sc. Medical Lab Technology April 2006 Advanced Lab. Techniques Question Paper PDF Download

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             LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

M.Sc. DEGREE EXAMINATION – MEDICAL LAB TECHNOLOGY

HZ 5

SECOND SEMESTER – APRIL 2006

                                               ML 2952 – ADVANCED LAB. TECHNIQUES

 

 

Date & Time : 24-04-2006/9.00-12.00         Dept. No.                                                       Max. : 100 Marks

 

 

Part A                                     (Answer All)                          10 ´ 2 = 20

  1. List out any four protein transfer procedure.
  2. What is ponceou S and PVDF?
  3. What are ramification amplification?
  4. Write the goals of HGP.
  5. Define gene therapy.
  6. Define obligatory paternal gene.
  7. What is direct exclusion?
  8. Define Two haplotype exclusion
  9. What is parentage testing?
  10. Expand the abbreviations: SWGDAM, FBI, CODIS, NDIS.

Part B                                     (Answer any four)                 4 ´ 10 = 40

  1. Write a short note on DNA polymorphism.
  2. Describe in brief human leukocyte antigen.
  3. Comment on documentation and reporting parentage-testing results.
  4. Describe in detail any two gene sequencing method.
  5. Give an account on human genome project.
  6. Describe in detail the micro array procedure and add a note on its clinical application.

 

Part C                                     (Answer any two)                              2 ´ 20 = 40

  1. Explain in detail the DNA testing method.
  2. Describe molecular techniques in the diagnosis of hematopoitic neoplasm.
  3. Write the importance of molecular techniques used in the diagnosis of leukemia.
  4. Discuss the techniques to detect antigen receptor gene rearrangement.

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Loyola College M.Sc. Medical Lab Technology Nov 2006 Statistical Applications In Biological Sciences Question Paper PDF Download

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                     LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

M.Sc. DEGREE EXAMINATION – BIOMED.INSTR.&MED.LABO.TECHNO.

AB 29

THIRD SEMESTER – NOV 2006

           ST 3901 – STATISTICAL APPLICATIONS IN BIOLOGICAL SCIENCES

 

 

Date & Time : 03-11-2006/9.00-12.00      Dept. No.                                                    Max. : 100 Marks

 

 

Part A

Answer all the questions.                                                                            10 X 2 = 20

 

  1. Define statistics.
  2.  What are the advantages of diagrammatic presentation of data?
  3. State the various measures of central tendency.
  4. Define dispersion.
  5. What do you understand by skewness and kurtosis?
  6. Explain the meaning and significance of the concept of correlation.
  7. Define statistic and parameter.
  8. What is type II error?
  9. Write any two uses of chi-square test.
  10. What is analysis of variance?

PART -B

Answer any five questions.                                                                           5 X 8 = 40

 

  1. Briefly explain the  scope, limitation and misuse of statistics.
  2. The following data relate to the monthly expenditure ( in rupees) of the families A and B:

Items of expenditure                           Family A         Family B

Food                                                    1600                1200

Clothing                                              800                  600

Rent                                                    600                  500

Light and Fuel                                                200                 100

Miscellaneous                                      800                  600

Represent the above data by a suitable percentage diagram.

  1. Calculate mean, median and standard deviation for the following data:

Age                 :           10-20   20-30   30-40   40-50   50-60   60-70

No. of death by HIV:    2          6          10        7           4          1

14.  Calculate Spearman’s coefficient of correlation between height and weight are given below:

Age     :           2          5          8          10        12        18        20        25

Weight:           4          8          15        28        32        45        50        60

 

  1. In a random sample of 1000 persons from city Trichy, 400 are found to be consumers of Hans. In a sample of 800 from city Tanjore , 400 are found to be consumers of tobacco. Do these data reveal a significant difference between city Trichy and Tanjore, so far as the proportion of tobacco is concerned?

 

 

  1. The following table shows the ages (X) and blood pressure (Y) of 8 persons.

X:        52        63        45        36        72        65        47        25

Y:        62        53        51        25        79        43        60        33

Obtain the regression equation of Y on X and find the expected blood pressure fo a person who is 49 years old.

  1. 500 apples are taken at random from a large basket and 50 are found to be bad. Estimate the proportion of bad apples in the basket and assign limits within which the percentage most probably lies.
  2. From the following table find is there any significance difference between treatments or not.
Treatment Treatment1 Treatment2 Treatment3 Treatment4
Kumar

Senthil

Saravanan

 80

70

68

 100

88

99

 110

96

79

 70

85

94

PART C

Answer any two questions.                                                                         2 X 20 = 40

 

  1. Explain different types of diagrams in statistics with an illustration.
  2. For a random sample of 10 persons, fed on diet A, the increased weight in pounds in a certain period were:

10        6          16        17        13        12        8          14        15        9

For another random sample of 12 persons, fed on diet B, the increase in same period were:

7          13        22        15        12        14        18        8          21        23        10    17

Test whether the diets A and B differ significantly as regards their effect on increase in weight.

Given the following data:

Degrees of freedom    :          19       20       21       22       23

Values of t at 5 % level:          2.09     2.09     2.08     2.07     2.07

 

  1. a). A certain drug is claimed to be effective in curing cold. In an experiment on 1000 persons with cold, out of which 250 were given the drug and 250 were given sugar pills. The patients reactions to the treatment are recorded in the following table:

 

Medicine         helped             harmed                        no effect          total

Drug                150                  30                    70                    250

Sugar pills       130                  40                    80                    250

On the basis of the data can it be concluded that there is a significant difference in

the effect of the drug  and sugar pills?

b). The average life span  of people in  Trichy district is 65 years with the

standard deviation of 4 years. Randomly 10 people were observed and their life

span were recorded:

45        60        75        72        68        63        65        68        70        71

Verify that is there any significance at 5 % level of signifance.

 

  1. Four students were selected randomly from II M.Sc medical lab technology and they were given by different types of medicine for curing viral fever. The following hours have been taken by the medicine to cure the diseases.

Student           medicine1       medicine2       medicine3       medicine4

      Senthil            0.30                 0.35                 0.40                 0.45

Ishwariya       0.50                 0.55                 0.46                 0.48

Kannan          0.10                 0.20                 0.25                 0.29

Sona                0.50                 0.40                 0.45                 0.30

Is there any significance difference between medicines and students for taking

hours to cure the disease?

 

 

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Loyola College M.Sc. Medical Lab Technology Nov 2006 Pharmaceutical Chemistry And Toxicology Question Paper PDF Download

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                       LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

M.Sc. DEGREE EXAMINATION – MEDICAL LAB. TECHNOLOGY

AH 08

THIRD SEMESTER – NOV 2006

                        ML 3875 – PHARMACEUTICAL CHEMISTRY AND TOXICOLOGY

 

 

Date & Time : 06-11-2006/9.00-12.00   Dept. No.                                                       Max. : 100 Marks

 

 

PART A

 

Answer all the questions                                                         (10×2=20 Marks)

 

  1. Give the difference between ‘invivo’ and ‘invitro’ analysis of drugs.
  2. Explain the terms : a) Pharmacology b) Pharmacophore c) Pharmacokinetics
  3. d) Pharmacodynamics
  4. What are the different isotopes of carbon? How is it useful in medicinal field?
  5. What is meant by ‘cut off point’? Give an example.
  6. What is meant by ‘Buffer’? Mention its significance in designing drugs.
  7. What are the four basic types of chemical interactions?
  8. Define Lamellae & Liminent.

8.What is meant by first pass biotransformation.

9.Define FAS.

  1. What is meant by Intraosseous route of administration?

 

PART B

 

Answer any four of the following:                                                        (4×10=40 Marks)

 

  1. Explain briefly with examples
  2. a) Preservatives b) Ointment bases  c) Colouring and sweetening agent in drugs.
  3. Explain the relationship between the chemcal structure and pharmacological activity

using alkyl and acidic groups in drugs.

  1. Discuss the importance of chelation in explaining the biological activity of

compounds.

  1. Discuss the factors influencing Toxicity.
  2. Explain the different methods of administering drugs.
  3. What are the applications of radioisotopes in biological sciences.

 

PART  C

 

Answer any two of the following:                                                         (2×20=40 Marks)

 

  1. a) Explain the classification of drugs with examples
  2. b) How is radioactivity measured by Geiger – Muller counters
  3. Enumerate the physiochemical constants for prediction of bio activities.

19.Classify teratogens and write short notes on

  1. Fetal alcohol Syndrome b)Phenytoin c)Thalidomide
  2. Explain the process of drug absorption.

 

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Loyola College M.Sc. Medical Lab Technology Nov 2006 Molecular Biology Question Paper PDF Download

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                   LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

M.Sc. DEGREE EXAMINATION – MEDICAL LAB. TECHNOLOGY

AH 03

FIRST SEMESTER – NOV 2006

ML 1809 – MOLECULAR BIOLOGY

 

 

Date & Time : 31-10-2006/1.00-4.00       Dept. No.                                                       Max. : 100 Marks

 

 

SECTION-A

Answer all the questions                                                       2X10=20marks

  1. Mention the role of topoisomerases?
  2. Draw the secondary structure of t-RNA
  3. What is Chargaff’s rule?
  4. Write notes on a) heterochromatin b) euchromatin
  5. List the different kinds of lysosomes and their functions
  6. What is RNA polymerase holoenzyme?
  7. What is photoreactivation repair mechanism?
  8.  Expand the abbreviations
  1. a) APC b) CDKS
  1. What is the role of tyrosine kinases in cancer?
  2.  What is Turner’s syndrome?

SECTION-B

Answer any four of the following                                        4X10=40marks

 

  1. Explain the special constraints relevant to genetic testing
  2. Explain the molecular structure of double stranded DNA.
  3. Describe the mechanism of transcription in eukaryotes.
  4. What are leading and lagging strands? List out the enzymes of DNA replication and their functions.
  5. Write a short note on viral oncogene.
  6. Give an account of on excision and recombination repair mechanisms.

SECTION-C

Answer any two of the following                                         2X20=40marks.

 

  1. Draw the eukaryotic cell and write notes on a) endoplasmic reticulum.
  1. b) golgi complex c) mitochondria.
  1. Explain in detail the process of protein synthesis in prokaryotes.
  2. Describe in detail the regulation of eukaryotic cell cycle.
  3. Explain in detail the active transport of materials across plasma membrane.

 

 

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Loyola College M.Sc. Medical Lab Technology Nov 2006 Medical Transcription Question Paper PDF Download

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             LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034  M.Sc. DEGREE EXAMINATION – MEDICAL LAB. TECHNOLOGY

AH 05

FIRST SEMESTER – NOV 2006

         ML 1952 – MEDICAL TRANSCRIPTION

 

 

Date & Time : 02-11-2006/1.00-4.00           Dept. No.                                                       Max. : 100 Marks

SECTION-A

Answer all the questions                                                       2X10=20 marks

  1. What is Ectopic pregnancy?
  2. What is amniocentesis?
  3. List any six useful reference resources for MT.
  4. What is Osteoporosis?
  5. What is fracture? Write any two types.
  6. What is abbreviation?
  7. What is operative report?
  8. Write the functions of testosterone?
  9. What is cataract?
  10. Differentiate plasma from serum.

SECTION-B

Answer any four of the following                                        4X10=40 marks

  1. Describe and draw a labeled diagram of skeletal system.
  2. Discuss briefly the basic rules for formation of medical words.
  3. Give an account on anatomy and physiology of gastroenterology.
  4. Describe and draw a neat diagram of human eye.
  5. Write a short note on any two glands involved in endocrine system.
  6. Write a short note on steps involved in medical transcription.

SECTION –C

Answer any two of the following                                         2X20=40 marks.

  1. Write short notes on any four:
    1. History and physical formatting
    2. Discharge summary
    3. Consultation
    4. Operative
    5. Chart note
    6. Radiology report
  1. Describe the structure and functions of male genitalia.
  2. Discuss parts of speeches with reference to medical transcription.
  3. Discuss the importance of medical terminology in MT.

 

 

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Loyola College M.Sc. Medical Lab Technology Nov 2006 Human Physiology Question Paper PDF Download

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             LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034  M.Sc. DEGREE EXAMINATION – MEDICAL LAB. TECHNOLOGY

AH 07

THIRD SEMESTER – NOV 2006

                                       ML 3801 – HUMAN PHYSIOLOGY

 

 

Date & Time : 27-10-2006/9.00-12.00         Dept. No.                                                       Max. : 100 Marks

 

 

SECTION-A

Answer all the questions                                                       2X10=20marks

  1. List the three types of human hair & their functions.
  2. What is sebum? How is it secreted?
  3. Draw the structure of a human tooth & write the dental formula with expansion.
  4. Define residual volume and functional residual capacity.
  5. What are the layers of epidermis?
  6. What is chloride shift?
  7. List the hormones that stimulate spermatogenesis & its functions.
  8. What is sinoatrial node?
  9. What is feed back mechanism in hormone secretion? Give an example.
  10.  List a few differences between arteries & veins.

SECTION-B

Answer any four of the following                                        4X10=40marks

 

  1. Explain the mode of absorption of electrolytes and water in digestive system.
  2. Describe the birth control methods in detail.
  3. Explain in detail the process of micturition.
  4. Draw and explain the structure of lungs.
  5. Explain the different phases of gastric secretion.
  6. Explain the mechanism of muscle contraction.

SECTION –C

Answer any two of the following                                         2X20=40marks.

 

  1. What are gonadotropins? Explain their role in reproduction.
  2. Explain the role played by digestive enzymes in detail.
  3. Draw the structure of nephron and explain the mechanism of urine formation.
  4. Draw the structure of integumentary system. Explain a) Glands   b)hair follicles.

 

 

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Loyola College M.Sc. Medical Lab Technology Nov 2006 Hospital Management Question Paper PDF Download

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                       LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

M.Sc. DEGREE EXAMINATION – MEDICAL LAB. TECHNOLOGY

AH 04

FIRST SEMESTER – NOV 2006

ML 1951 – HOSPITAL MANAGEMENT

 

 

Date & Time : 02-11-2006/1.00-4.00     Dept. No.                                                       Max. : 100 Marks

 

 

 

PART A

 

Answer all the questions                                                         (2×10=20 Marks)

 

  1. What are the objectives of out -patient service department?
  2. List the records to be maintained in casualty and emergency departments.
  3. What is the need for Human Resource Development?
  4. What are the functions of Materials Management Department?
  5. Define Inventory.
  6. What is a balance sheet?
  7. What are the two systems of book keeping?
  8. Define a medical record.
  9. What is meant by “public” in relation to hospital environment?
  10. What are the factors involved in Good ward management?

 

PART B

 

Answer any four of the following:                                          (10×4=40 Marks)

 

  1. What is the role of an Administrator in Hospital environment? Explain.
  2. Explain the European Model of Operation Theatre.
  3. Define Job Satisfaction. Explain its consequences.
  4. Explain in detail the principles involved in Material Handling.
  5. What is a ware house? What are its functions?

16.What is quality assurance? Discuss the role of quality management in a hospital.

 

PART  C

 

Answer any two of the following:                                             (20×2=20 Marks)

17. Explain the process and techniques of Performance Appraisal System.

18. What do you mean by ABC analysis? Explain its utility in Inventory Management.

  1. Discuss the purpose, function and importance of Medical Records.
  2. Write an essay on Hospital Waste Management.

 

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Loyola College M.Sc. Medical Lab Technology Nov 2006 Haematology Question Paper PDF Download

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                          LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034                                         M.Sc. DEGREE EXAMINATION – MEDICAL LAB. TECHNOLOGY

AH 01

FIRST SEMESTER – NOV 2006

ML 1803 – HAEMATOLOGY

 

 

Date & Time : 26-10-2006/1.00-4.00     Dept. No.                                                       Max. : 100 Marks

 

 

SECTION-A

Answer all the questions                                                         2X10=20 marks

  1. What is iron deficiency anemia?
  1. What is Spherocytosis?
  2. Define quality assurance.
  3. Expand MCH, MCV, MCHC and SLE
  4. Give the normal value of cells present in differential count.
  5. What are granulocytes?
  6. What is Von Willebrand’s disease?
  7. What is platelet plug formation?
  8. What is Vasoconstriction?
  9. List the components of blood.

SECTION-B

Answer any four of the following                                              4X10=40 marks

 

Write a short note on red cell indices.

  1. Give the importance of bleeding time.
  2. Write a short note on cytochemical tests.
  3. Explain briefly the significance of thrombin time.
  4. Discuss the importance of Platelet count
  5. Give an account on the principle and procedure for the estimation of haematocrit.

SECTION –C

Answer any two of the following                                               2X20=40 marks.

  1. Describe in detail types of anaemia in human.
  2. Explain in detail “Lupus erythematous cell preparation”.
  3. Give an account on the importance of quality control and quality assessment in a clinical laboratory.
  4. Write in detail on granulopoiesis and agranulopoiseis.

 

 

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Loyola College M.Sc. Medical Lab Technology Nov 2006 Fluid Analysis Question Paper PDF Download

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                  LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034        M.Sc. DEGREE EXAMINATION – MEDICAL LAB. TECHNOLOGY

AH 06

THIRD SEMESTER – NOV 2006

ML 3800 – FLUID ANALYSIS

 

 

Date & Time : 25-10-2006/9.00-12.00         Dept. No.                                                       Max. : 100 Marks

 

 

 

PART A

 

Answer all the questions                                                         (2×10=20 Marks)

 

1.Write the equation used to measure blood volume.

  1. Define Spina Bifida and Myelomeningocele.
  2. What is APT test?
  3. What are the different membranes covering the brain and spinal cord?
  4. What is Xanthochromia?
  5. Define synovial fluid.

7.What are Char cot’s joints?

  1. What is Lupus?
  2. How will you classify effusions?

10.What are Chylomicrons?

 

PART B

 

Answer any four of the following:                                                            (10×4=40 Marks)

 

  1. Write briefly on Hyponatremia and Hypernatremia.
  2. How is the volume of fluid measured in the different body fluid compartments?
  3. Discuss how the fetal maturity is determined by the analysis of amniotic fluid.
  4. Explain Lumbar Puncture and the values seen in normal LP.
  5. Classify Synovial Fluid and its Associated diagnosis.
  6. Explain the mechanism of formation of urine.

 

PART C

 

Answer any two of the following:                                                              (20×2=20 Marks)

  1. Explain in detail the exchange of water in between compartments and how it is

maintained.

  1. Discuss in detail the formation and movement of CSF.
  2. What is rheumatoid arthritis? Discuss its causes, symptoms and diagnosis.
  3. What are the important constituents of Gastric juice? Add a note on Gastric

Motility Breath test.

 

 

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Loyola College M.Sc. Medical Lab Technology Nov 2006 Clinical Biochemistry Question Paper PDF Download

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                        LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

M.Sc. DEGREE EXAMINATION – MEDICAL LAB. TECHNOLOGY

AH 02

FIRST SEMESTER – NOV 2006

ML 1808 – CLINICAL BIOCHEMISTRY

(Also equivalent to ML 1801)

 

 

Date & Time : 28-10-2006/1.00-4.00      Dept. No.                                                       Max. : 100 Marks

 

 

PART-A

Answer all the questions                                                                   (10 x 2 = 20)

  1. Distinguish metabolic acidosis and respiratory acidosis.
  2. Draw hazard symbol of very toxic and irritant compounds.
  3. What is Embden-Meyerhof pathway?
  4. Write the function of parafollicular C cells in the thyroid gland.
  5. Name the marker compound present in the colon, pancreatic, breast and ovarian cancers.
  6. What is reverse cholesterol transport process?
  7. Draw the structure of haemoglobin.
  8. What is the antioxidant property of Vitamin E?
  9. Expand the abbreviations: PSA, BTA, and APAF.
  10. Define the term: Ochronosis.

PART-B

Answer any four of the following                                                    (4 X 10 = 40)

  1. What are cardiac enzymes? Explain their functions and clinical significance.
  2. Write a short note on pancreatic function test.
  3. Describe in detail the synthesis and biochemical functions of thyroid hormones.
  4. What are non-protein nitrogen substances? Add a note on urea formation.
  5. Describe in detail the renal function test.
  6. Give the normal values and biological importance of electrolytes Na+, K+, Cl–, Ca2+ and Mg2+.

PART – C

Answer any two of the following                                                     (2 X 20 = 40)

  1. Write an essay on the enzymes of gastrointestinal tract involved in the digestion of

carbohydrates and proteins.

  1. Explain citric acid cycle with structure and regulatory mechanism.
  2. What is lipid profile? Write the principle, procedure, normal value and clinical

significance of any three lipid profile test.

  1. Describe in detail the difference laboratory investigations employed to assess liver function.

 

 

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Loyola College M.Sc. Mathematics April 2006 Topology Question Paper PDF Download

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             LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

M.Sc. DEGREE EXAMINATION – MATHEMATICS

CV 10

THIRD SEMESTER – APRIL 2006

                                                                  MT 3800 – TOPOLOGY

 

 

Date & Time : 28-04-2006/1.00-4.00 P.M.   Dept. No.                                                       Max. : 100 Marks

 

 

Answer ALL questions.  All questions carry equal marks.

  1. a) i) Let X be a metric space with metric d.  Show that d1 defined by  is also a metric on X.  Give an example of a pseudo metric which is not a metric.

(or)

  1. ii) In any metric space X, show that each open sphere is an open set.  Prove that any union of open sets in X is open.                                                                                                                 (8)
  2. b) i) Let X be a complete metric space and let Y be a subspace of X.  Prove that Y is complete iff it is closed.
  3. ii) State and prove Cantor’s Intersection Theorem.

iii)  If  is a sequence of nowhere dense sets in a complete metric space X, prove that there exists a point in X which is not any of the s.                                                               (6+6+5)

  1. iv) Let X and Y be metric spaces and f be a mapping of X into Y.  Then prove that f is continuous iff is open in X whenever G is open in Y.
  2. v) Prove that the set C(X,R) of all bounded continuous real functions defined on a metric space X is a Banech space with respect to point wise addition and scalar multiplication and the norm defined by .                                                                                                                  (6+11)
  3. a) i) Show that every separable metric space is second countable.

(or)

  1. ii) Prove that the product of any non-empty class of compact spaces is compact.

(8)

  1. b) i) Show that any continuous image of a compact space is compact.
  2. ii) Prove that any closed subspace of a compact space is compact.

iii)  Give an example to show that a compact subspace of a compact space need not be closed.         (6+6+5)

(or)

  1. State and prove Lindelof’s Theorem.
  2. v) Let X be any non-empty set, and let S be an arbitrary class of subsets of X.  Show that S can serve as an open subbase for a topology on X.                                                            (6+11)

III. a) i)   Prove that a metric space is compact iff it is complete and totally bounded.

(or)

  1. ii) Prove that every compact Hausdorff space is normal.                                     (8)
  2. b) i) In a sequentially compact metric space, prove that every open cover has a Lebesque number.
  3. ii) Show that every sequentially compact metric space is totally bounded.

iii)  Prove that every sequentially compact metric space is compact.             (9+4+4)

(or)

  1. b) iv) In a Hausdorff space, show that any point and disjoint compact subspace can be separated by open sets.
  2. v) Show that every compact subspace of a Hausdorff space is closed.
  3. vi) Prove that a 1–1 mapping of a compact space on to a Hausdorff space is homeomorphism.         (7+5+5)
  4. a) i) Prove that any continuous image of a connected space is connected.

(or)

  1. ii) Let X be a T1  Prove that X is normal iff each neighbourhood of a closed set F contains the closure of some neighbourhood of F.                                                                           (8)
  2. b) i) State and prove the Urysohn Imbedding Therorem.

(or)

  1. ii) State and prove the Weierstrass Approximation Theorem.                            (17)

 

 

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Loyola College M.Sc. Mathematics April 2006 Probability Theory And Stochastic Processes Question Paper PDF Download

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             LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

M.Sc. DEGREE EXAMINATION – MATHEMATICS

SECOND SEMESTER – APRIL 2006

                       ST 2902 – PROBABILITY THEORY AND STOCHASTIC PROCESSES

 

 

Date & Time : 28-04-2006/9.00-12.00         Dept. No.                                                       Max. : 100 Marks

 

 

PART – A

Answer ALL the questions                                                                                                              (10 ´ 2 = 20)

  1. Define probability by classical method.
  2. Give an example for a discrete probability distribution.
  3. Define an induced probability space.
  4. State the properties of a distribution function.
  5. Define the distributed function of a continuous random variable.
  6. Write the formula to find the conditional mean and variance of Y given X = x.
  7. What do you mean by a Markov matrix? Give an example
  8. Write a note on one-dimensional random walk.
  9. Define (i) recurrence of a state           (ii) periodicity of a state
  1. Define renewal function.

PART – B

Answer any FIVE questions.                                                                                                             (5 ´ 8 = 40)

  1. State and prove Boole’s inequality.
  2. Explain multinomial distribution with an example.
  3. Given the dF

F(x) =       0     ,  x < – 1

 

=    ,  -1

=      1        ,  1

 

compute (a) P(-1/2 < X  1/2)         (b) P(X = 0)    (c) P(X = 1)       (d) P (2 < X  3).

 

  1. Let X have the pdf f(x) = 2x,  0 < x < 1, zero elsewhere. Find the dF and p.d.f. of Y = X2.

 

  1. (a) When is a Markov process called a Markov chain?

(b) Show that communication is an equivalence relation.                                                              (2 + 6)

 

  1. A Markov chain on states {0,1,2,3,4,5} has t.p.m.

 

Find the equivalence classes.

 

  1. Find the periodicity of the various states for a Markov chain with t.p.m.

 

 

 

 

  1. Derive the differential equations for a pure birth process clearly stating the postulates.

 

PART – C

Answer any TWO questions.                                                                                                           (2 ´ 20 = 40)

 

  1. (a) The probabilities that the independent events A,B and C will occur are ¼, ½ , ¼ respectively.
    What is the probability that at least one of the three events will occur?

 

  • Find the mean and variance of the distribution that has the dF

 

F(x)  =  0         ,  x < 0

=  x/8      ,  0  £  x < 2

=  x2/16   ,  2  £  x < 4

=  1         ,  4  £  x                                                                                                     (5 + 15)

 

  1. If X1 and X2 have the joint p.d.f.

 

f(x1,x2) =

 

find     (i) marginal pdf of X1 and X2.

                                                (ii) conditional pdf  of X2 given X1 = x1 and X1 given X2 = x2.

(iii) find the conditional mean and variance of X2 given X1 = x1 and

X1 given X2 = x2.                                                                                                                  (4 + 4 + 12)                      

 

  1. Derive a Poisson process clearly stating the postulates.

 

  1. Derive the backward and forward Kolmogorov differential equations for a

birth and death process clearly stating the postulates.

 

 

 

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Loyola College M.Sc. Mathematics April 2006 Mathematical Statistics – II Question Paper PDF Download

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             LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

M.Sc. DEGREE EXAMINATION – MATHEMATICS

AC 50

FOURTH SEMESTER – APRIL 2006

                                              ST 4900 – MATHEMATICAL STATISTICS – II

(Also equivalent to ST 4953)

 

 

Date & Time : 03-05-2006/9.00-12.00         Dept. No.                                                       Max. : 100 Marks

 

 

SECTION-A    (10 ´ 2 = 20)

Answer ALL questions.  Each question carries 2 marks.

  1. Let T have a t-distribution with 10 degrees of freedom. Find P(|T|  > 2.228).
  2. Find the variance of S2 = (1/n) ∑ ( xi – x )2 , when X1, X2,…., Xn is a random sample      from N(µ , σ2 ).
  3. How do you obtain the joint p.d.f. of any two order statistics Yr and Ys when Yr < Ys ?
  4. What do you understand by a sufficient statistic for a parameter?
  5. Define: UMVUE.
  6. State Rao-Cramer Inequality.
  7. Distinguish between randomized and non-randomized tests.
  8. Illustrate graphically, the meaning of UMPT of level α test.
  9. Define a renewal process.
  10. When do you say that a stochastic matrix is regular?

SECTION-B   (8 x 5 = 40)

Answer any 5 questions.  Each question carries 8 marks.

 

  1. Let and S2 be the mean and the variance of a random sample of size 25 from a distribution N (3, 100).   Evaluate P (0 < < 6, 55.2 < S2 < 145.6).
  2. Derive the central F-distribution with (r1, r2) degrees of freedom.
  3. Let Y1 < Y2 < Y3 be the order statistics of a random sample of size 3 from the uniform distribution having p.d.f.
    f(x; θ ) = 1/θ, 0 < x < θ, 0 < θ < ∞, zero elsewhere.  Show that 4Y1, 2Y2 and (4/3)Y3 are all unbiased estimators of θ.  Find the variance of  (4/3)Y3.
  4. If az2 + bz + c = 0 for more than two values of z, then show that a = b = c = 0. Use this result to show that the family{ B(2, p): 0 < p < 1}  is complete.
  5. State and prove Lehmann-Scheffe’s theorem.
  6. Let X have a p.d.f. of the form f(x; θ) = θ xθ-1 , 0 <x < 1,  θ =1,2, zero elsewhere.  To test H0 : θ =1 against H1: θ =2, use a random sample X1, X2 of size n = 2 and define the critical region to be C = { (x1, x2) : ¾ ≤ x1­ x2 }.  Find the power function of the test.
  7. Prove or disprove: “UMPT of level α always exists for all types of testing problems”. Justify your answer.
  8. A certain genetic model suggests that the probabilities of a particular trinomial distribution are, respectively, p1 =p2, p2 = 2p (1-p), and p3 = (1-p)2 , where  0 < p < 1.   If X1, X2, X3 represent the respective frequencies in ‘n’ independent trials, explain how we could check on the adequacy of the genetic model.

 

SECTION-C       ( 20 ´ 2 = 40 )

Answer any 2 questions. Each question carries 20 marks.

  1. a) State and prove Factorization theorem. (12)
  2. b) Given the p.d. f.  f(x; θ) = 1 / ( π [1 + ( x – θ)2 ) , -∞ < x  < ∞ , -∞ < θ <  ∞. Show that the Rao-Cramer lower bound  is 2/n, where n is the size of a random sample from this Cauchy distribution. (8)

 

  1. a) State and prove the sufficiency part of Neyman-Pearson theorem. (12)
  2. b) Let X1, X2,…, Xn denote a random sample from a distribution having the p.d.f.
    f(x; p) = px (1-p)1-x , x = 0,1, zero, elsewhere.  Show that C =  { (x1, …,xn) :  Σ xi ≤ k }is a best critical region for testing H0: p = ½ against  H1: p = 1/3. Use the central limit theorem to find n and k so that approximately the level of the test is 0.05 and the power of the test is 0.9. (8)

 

  1. a) Derive the likelihood ratio test for testing H0: θ1=0, θ2 > 0 against
    H1: θ1 ≠ 0,  θ2 >0  when a random sample of size n is drawn from N(θ1 , θ2 ). (12)
  2. b) By giving suitable examples, distinguish between unpaired and paired t-tests. (8)

 

  1. a) Show that the Markov chain is completely determined by the transition matrix and the initial distribution. (8)
  2. b) Give an example of a random walk with an absorbing barrier.  (4)
  3. c) Explain in detail the properties of a Poisson process. (8)

 

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Loyola College M.Sc. Mathematics April 2006 Mathematical Statistics – I Question Paper PDF Download

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             LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

M.Sc. DEGREE EXAMINATION – MATHEMATICS

 

THIRD SEMESTER – APRIL 2006

                                               ST 3951 – MATHEMATICAL STATISTICS – I

 

 

Date & Time : 27-04-2006/1.00-4.00 P.M.   Dept. No.                                                       Max. : 100 Marks

 

 

     SECTION-A    (10 ´ 2 = 20)

Answer ALL questions.  Each question carries 2 marks.

  1. Give an example for a non-decreasing sequence of sets.
  1. Distinguish between experiment and random experiment.
  2. Let f (x) =    x/15,  x=1,2,3,4,5

0,  otherwise.

Find the median of the above distribution.

  1.  Let f(x) = (4-x) / 16, -2 < x < 2 ,zero elsewhere, be the p.d.f. of X.

If Y = ‌ X ‌ , compute P(Y ≤ 1).

  1. Give an example of a random variable in which mean doesn’t exist.
  1. Prove that E(E(X / Y)) = E(X).
  2. Define Hyper Geometric distribution.
  3. Define the characteristic function of a multidimensional random vector.

p                         p                                                 p

  1.  If    Xn → X    and    Yn →   Y, then show that Xn + Yn   →   X +Y.
  2. State Lindeberg-Feller theorem.

SECTION-B   (8 x 5 = 40)

Answer any 5 questions.  Each question carries 8 marks.

  1. Let f(x) = ½, -1 < x < 1, zero elsewhere, be the p.d.f. of X.  Find the distribution

function and the p.d.f. of Y = X2.

  1. State and prove Chebyshev’s inequality.
  2. If X1 and X2 are discrete random variables having the joint p.m.f.

f(x1,x2) = ( x1 + 2 x2 ) / 18,  (x1, x2­) = (1,1), (1,2), (2,1), (2,2), zero elsewhere, determine the conditional mean and variance of X2, given X1 =x1, for x1 = 1 or 2.

Also, compute E[ 3X1 – 2 X2 ].

  1. State and prove any two properties of MGF.
  2. Stating the conditions, show that binomial distribution tends to Poisson

distribution.

  1. Obtain the central moments of N (µ, σ2).
  2. Let X ~ G (n1, α) and Y ~ G (n2, α) be independent. Find the distribution of X/Y.
  3. Explain in detail the difference between WLLN and SLLN.

 

                                           SECTION-C ( 20 x 2 = 40 )

Answer any 2 questions. Each question carries 20 marks.

  1. a) State and prove Bayes’ theorem. (10)
  2. b) Bowl I contains 3 red chips and 7 blue chips. Bowl II contains 6 red chips and 4 blue chips. A bowl is selected at random and then 1 chip is drawn from this bowl.  Compute the probability that this chip is red.  Also, relative to the hypothesis that the chip is red, find the conditional probability that is drawn from bowl II.  (10)

 

  1. a) Find the mean and variance of the random variable X having the distribution function:

 

F(x)   =   0,        x < 0,

( x/4),   0≤x <1,

(x2 /4), 1≤x<2,

1 ,        x≥ 2.                                                  (10)

  1. b) Let X have the uniform distribution over the interval ( -π/2 , π/2). Find the

distribution of Y  = tan X.    (10)

 

  1. a) State and prove Kolmogorov’s strong law of large numbers. (12)
  2. b) State and prove Borel-Cantelli lemma. (8)

 

  1. a) Examine if central limit theorem (using Lyapounov’s condition) holds for the

following sequence of independent variates:

 

 

P     Xk   =   ±  2k      =   2-(2k + 1) ,             P       Xk  =  0    =   1 – 2–2k   (8)

 

  1. b) State and prove Lindeberg-Levy central limit theorem. (12)

 

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Loyola College M.Sc. Mathematics April 2006 Functional Analysis Question Paper PDF Download

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             LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

M.Sc. DEGREE EXAMINATION – MATHEMATICS

CV 5

FOURTH SEMESTER – APRIL 2006

                                                      MT 4800 – FUNCTIONAL ANALYSIS

 

 

Date & Time : 20-04-2006/FORENOON     Dept. No.                                                       Max. : 100 Marks

 

 

ANSWER ALL QUESTIONS

  1. a) i) Show that every vector space has a Hamel basis

(or)

  1. ii) If f Î X*, prove that the null space Z(f) has deficiency 0 or 1 in X.  Conversely, show that if Z is a subspace of X of deficiency 0 or 1, then there is an f Î X* such that Z=Z(f).
  2. b) iii)   Show that every element of X/Y contains exactly one element of Z, where Y and Z are complementary subspaces of X.
  3. iv) Let X and Y be normed linear spaces and let B(X, Y) denote the set of all bounded linear transformations from X into Y.  Then prove that B(X,Y) is a normed linear space.

(or)

  1. v) Let X be a real vector space, p be a real valued function on X such that P(x+y) £ p(x) + p(y) and p(ax) = a p(x) ” x,y Î X and a ³ 0, and let Y be a subspace of X.  If f is a linear functional on Y and f(x)  £  p(x) ” x Î Y, prove that there is a linear functional F on X such that F(x)=f(x)  ” x Î Y and F(x) £ p(x) ” x Î
  2. a) i) If x ¹ 0 is an element of a real normed linear space X, then show that there exists an x Î x¢ such that x¢(x) = ||x||  and ||x¢|| = 1.

(or)

  1. ii) Let X and Y be Banach spaces and let T be a linear transformation of X into Y.  Prove that if the graph of T is closed, then T is bounded.                                                                   (8)

(or)

  1. b) iii)   State and prove the uniform boundedness theorem.
  2. iv) Give an example to show that uniform boundedness principle is not for every normed vector space.                                                                                                             (10+7)

(or)

  1. v) Let X and Y be Banach spaces and if T is a continuous linear transformation of X onto Y, then prove that T is an open mapping.                                                                               (17)
  2. a) i) State and prove the Riesz – Representation Theorem.

(or)

  1. ii) If M and N are closed linear subspaces of a Hilbert space X and if P and Q are projections on M and N, then show that M ^N Û PQ = 0 Û QP=0                                               (8)
  2. b) iii)   If T is an operator on a Hilbert space X, then prove that T is normal iff its real and imaginary parts commute.
  3. iv) Prove that how Hilbert spaces are isomorphic iff they have the same dimension.  (7+10)

(or)

  1. v) If P is a projection on a closed linear space M of a Hilbert space X, prove that M is invariant under T Û TP =PTP
  2. vi) If P1, P2, … Pn are projections on closed linear subspaces M1, M2, … Mn on X, then prove that P= P1 + P2 + …+Pn is a projection iff the Pi are pairwise orthogonal and in the case P is a projection on M=M1+M2+…+Mn.                                                                              (5+12)
  3. a) i) Prove that every element x in a Banech algebra A for which ||x–1|| < 1, is regular, and the inverse of such an element is given by .

(or)

  1. ii) Let A be a Banech algebra and x Π Then prove that the spectrum of x, s(x), is non-empty.   (8)
  2. b) iii)   Let G be the set of regular elements in A and S be the set of singular elements in A.  Prove that G is an open set and therefore S is a closed set.
  3. iv) Show that the mapping x à x–1 of G into G is continuous and is therefore a homeomorphism.   (5+12)

(or)

  1. v) State and prove the Spectral Theorem.                                                    (17)

 

 

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