LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
M.Sc. DEGREE EXAMINATION – MEDICAL LAB. TECHNOLOGY
FIRST SEMESTER – APRIL 2012
ML 1808 – CLINICAL BIOCHEMISTRY
Date : 25-04-2012 Dept. No. Max. : 100 Marks
Time : 9:00 – 12:00
Section – A
Answer ALL questions. 10 x 2 = 20 Marks
- Comment on Cretinism and myxoedema.
- What is gluconeogenesis?
- Write the importance of enzyme thyroperoxidase.
- What are lipoproteins?
- Name the abnormal hemoglobins.
- What is urea clearance test?
- Comment on Gaucher’s disease?
- Write down the principle of Van den Bergh reaction.
- What is Von Willebrand syndrome?
- Name any four hormones which act as a tumor markers.
Section – B
Answer any FOUR of the following 4 x 10 = 40 Marks
- Classify and explain the different types of laboratory chemicals.
- Write short notes on cardiac markers.
- Enumerate the importance of endocrine system and its disorders.
- Give an account of types, structure and function of hemoglobin.
- What is Achylia gastric? Explain any three gastric function tests.
- Describe the clinical importance of tumor markers with suitable example.
Section – C
Answer any TWO of the following 2 x 20 = 40 Marks
- Describe the mechanism of blood coagulation.
- Discuss the different laboratory investigations to evaluate liver function.
- Explain the metabolic pathway of glycolysis and TCA cycle.
- Elaborate the newborn disorders of carbohydrate and amino acid metabolism.