LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
B.Sc. DEGREE EXAMINATION – PLANT BIOLOGY & PLANT BIO-TECH.
FIFTH SEMESTER – NOVEMBER 2012
PB 5406 – IMMUNOLOGY AND IMMUNOTECHNOLOGY
Date : 10/11/2012 Dept. No. Max. : 100 Marks
Time : 9:00 – 12:00
Part A
Answer the following each within 50 words: (10 x 2 =20)
- Enlist the contributions of Louis Pasteur.
- Define passive immunity.
- What is a paratope ?
- Define opsonization.
- What is agglutination?
- Define immunodiffusion.
- Mention the function of bone marrow.
- What is meant by cell-mediated immunity?
- Define antiserum.
- What are polyclonal antibodies?
PART B
Answer the following within 500 words. Draw diagrams wherever necessary: (5 x7 = 35)
- (a) Write short notes on the contributions of Edward Jenner.
(or)
(b) Describe briefly the process of acquired immunity.
- (a) List elaborately the essential factors for antigenicity.
(or)
(b) Elucidate the structure of immunoglobulin.
- (a) Write short notes on ELISA and its applications.
(or)
(b) Explain the principle and process of counter current immunoelectrophoresis.
- (a) Describe briefly the B-lymphocytes with suitable diagram.
(or)
(b) Give a short account on cytokines and their functions.
- (a) Enumerate the applications of monoclonal antibodies.
(or)
(b) Describe briefly the production and application of antisera.
Part C
Answer any three of the following each within 1200 words. Draw diagrams wherever necessary: (3x 15 =45)
- Describe in detail the principles and factors involved in innate immunity.
- What are antibodies? Explain in detail the various classes of antibodies.
- Give a detailed account on Western blotting and its applications.
- List the types of complement pathways and explain any one in detail.
- Give an account on the hybridoma technology and its applications.
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