M.Sc Medical Lab Technology Question Paper
Loyola College M.Sc. Medical Lab Technology April 2006 Tissue Culture Question Paper PDF Download
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
M.Sc. DEGREE EXAMINATION – MEDICAL LAB TECHNOLOGY
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FOURTH SEMESTER – APRIL 2006
ML 4951 – TISSUE CULTURE
Date & Time : 22-04-2006/9.00-12.00 Dept. No. Max. : 100 Marks
Part A (Answer All) 10 X 2 = 20
- What is single cell culture?
- What is the possible mechanism leading to somoclonal variation?
- Classify suspension culture.
- Give two examples of secondary cell lines.
- What are the cryopreservatives used to preserve cells?
- What type of instruments is used for plant tissue culture?
- Give the basic composition of a plant tissue culture medium
- What are the different categories of organ culture?
- What is micropropagation?
- Define somatic hybridization.
Part B (Answer any four) 4 X 10 = 40
- Explain leaf culture.
- Give a general account of the expression of totipotency of cells in a culture.
- Discuss the importance of artificial seeds
- How is the growth of virus detected in cell culture?
- What are cell lines? Explain the different types.
- Briefly discuss lymphocyte separation.
Part C (Answer any two) 2 X 20 = 40
- Describe the principle & application of root culture techniques mentioning the protocol for root culture.
- Discuss the different types of protoplast fusion
- What are phytohormones? Discuss its importance.
- Describe the methodology & Importance of anther and pollen culture.
Loyola College M.Sc. Medical Lab Technology Nov 2003 Clinical Diaynostic Microbiology Question Paper PDF Download
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI– 600 034
M.Sc. DEGREE EXAMINATION -medical laboratory technology
FIRST SEMESTER – NOVEMBER 2003
ML 1805 clinical diaynostic microbiology
11.11.2003 Max: 100 Marks
1.00 – 4.00
SECTION – A
Answer ALL the questions (10 ´ 2 = 20 Marks)
- What is the function of capsules and slime layers?
- Define toxins and how is their potency expressed?
- What are differential stains?
- What is metachromasia?
- What are the different kinds of media?
- What is an enrichment medium?
- Define sterilisation.
- What are bactericidal and bacteriostatic agents?
- What is sanitization?
- Define virulence.
SECTION – B
Answer any four of the following (4 ´ 10 = 40 Marks)
- Describe the composition and structure of peptidoglycan, gram positive
and gram negative cell walls.
- Explain the structure of flagella and its distribution patterns.
- What are the three types of nutrient broth and how will you prepare them?
- What are disinfectants? What are the various applications of disinfectants?
- Discuss the spread and outbreak of infections in a community.
- Explain the infective hazards of intravenous infusion therapy.
SECTION – C
Answer any two of the following. (2 ´ 20 = 40 Marks)
- Define bacteraemia and explain on gram positive and gram
negative bacteraemia.
- Discuss in detail the special staining methods of flagella,
capsule, spores and granules with suitable diagrams.
- List the various physical methods of sterilisation and explain sterilisation by heat.
- Give an account on control and prevention of hospital acquired infections.
Loyola College M.Sc. Medical Lab Technology Nov 2003 Clinical Biochemistry Question Paper PDF Download
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI– 600 034
M.Sc. DEGREE EXAMINATION -medical laboratory technology
FIRST SEMESTER – NOVEMBER 2003
ML 1801 clinical BIOCHEMISTRY
06.11.2003 Max: 100 Marks
1.00 – 4.00
SECTION – A
Answer the following in ONE or TWO sentence (10 ´ 2 = 20 Marks)
- Differentiate glycogenolysis, from gluconeogenesis.
- Urea and Uric acid are the end products of __________.
- What is tetany and Gout?
- What is dysyuris and anuria?
- What are the isoenzymes of C.P.K name them and where is it found?
- What is the difference between a colorimeter and spectrophoto meter?
- Name the hormones which regulate blood sugar.
- What is the level of urea and creatinine in renal, prerenal and post renal conditions?
- Name and water soluble and FGT soluble vitamins with their function.
- Expand ACTH, PTH, S.G.O.T & S.G.P.T.
SECTION – B
Answer any four of the following (4 ´ 10 = 40 Marks)
- What is the importance of Alkaline phosphatase? What are the isoemzymes
of alkaline phosphatase? Give a brief account of their physiological role.
- Give in tabular form the levels of calcium, phosphorous alkaline phosphatase
and urinary calcium in any ten forms of disease.
- List the liver function test in case of obstructive, hepatocellular and transfusion reactions.
- What is toxiocology? Give any five substances with their dosage and effects in tabular form.
- What are electrolytes? State their importance.
- What is glycosylated haemoglobin? What is its importance in diabetes?
SECTION – C
Answer any TWO of the following (2 ´ 20 = 40 Marks)
- What are the cardiac enzymes? Name them in order and describe.
- Describe a colorimeter diagramatically, name the parts and give the corresponding filters used and how does it differ from spectrophotometer diagramatically.
- What is amylase and acid phosphatse? Give in detail their mode of action and implications.
- What is lipid profile? Give the lipid classification by fredrickson and explain the conditions.
Loyola College M.Sc. Medical Lab Technology Nov 2003 Essentials Of Clinical Laboratory Question Paper PDF Download
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI– 600 034
M.Sc. DEGREE EXAMINATION -medical laboratory technology
FIRST SEMESTER – NOVEMBER 2003
ML 1800 essentials of clinical laboratory
04.11.2003 Max: 100 Marks
1.00 – 4.00
SECTION – A
Answer All the questions. (10 ´ 2 = 20 Marks)
- Mention the role of Iris diaphragm in a compound light microscope.
- Write the procedure for collection of sputum in a clinical laboratory.
- What is phlebotomy?
- Mention the use of Sahli’s pipette, Westegren tube and wintrobe tube.
- Define the units of measurements: ml, pg, fg and g/dl.
- Write the format of a laboratory register.
- What is autoclave?
- Write the procedure in preparation of 1.0N Hcl solution.
- Write the composition of Hayem’s fluid.
- Define the term “Medical Ethics”.
SECTION – B
Answer any four of the following (4 ´ 10 = 40 Marks)
- Give an account of basic needs of a laboratory.
- Write the procedure for capillary puncture and venipuncture during phlebotomy.
- Write the format of a laboratory requisition sheet of a typical clinical laboratory.
- Write the procedure in preparation of laboratory reagents, citing an example for each type.
- Summarise the techniques of any five laboratory operations.
- Write the various aspects of care of a laboratory.
SECTION – C
Answer any TWO of the following (2 ´ 20 = 40 Marks)
- Give an account of various components of a laboratory.
- Write an essay on types laboratory accidents.
- Explain in detail quality control of laboratory findings. Add a note on quality control chart.
- Describe different types of microscopes and their uses in clinical laboratory.
Loyola College M.Sc. Medical Lab Technology Nov 2003 Haematology Question Paper PDF Download
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI– 600 034
M. Sc. DEGREE EXAMINATION -medical laboratory technology
FIRST SEMESTER – NOVEMBER 2003
ML 1803 haematology
08.11.2003 Max: 100 Marks
1.00 – 4.00
SECTION – A
Answer ALL the questions (10 ´ 2 = 20 Marks)
- Draw and label any four abnormal type of Red blood corpuscles.
- List the disorders related to Haemostasis.
- What is prothrombin Time?
- Distinguish quality control from quality assessment.
- What is aplastic anaemia?
- Differentiate coagulation from agglutination.
- Write the normal values of PCV, ESR, reticulocyte count and absolute
eosinophil count.
- What are Heinz bodies?
- Define the term-Lupus erythematosus.
- What is purpura?
SECTION – B
Answer any four of the following (4 ´ 10 = 40 Marks)
- Give an account of cell components of the blood.
- Explain the regulatory mechanism of Haemostasis.
- Give an account of red blood cell indices.
- Write the principle and procedure in the estimation of platelet count.
- Write the principle and the procedure of osmotic fragility test.
- Summarise the cytochemical tests carried out in the haematology laboratory.
SECTION – C
Answer any TWO of the following (2 ´20 = 40 Marks)
- Write an essay on haemopoietic system of the body.
- Describe in detail blood coagulation mechanism.
- Write the principle, procedure, calculation and normal value of total RBC count.
Add a note an clinical importance.
- Give an account of types of anaemia and their clinical relevance.
Loyola College M.Sc. Medical Lab Technology April 2006 Non Invasive Techniques Question Paper PDF Download
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
M.Sc. DEGREE EXAMINATION – MEDICAL LAB TECHNOLOGY
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FOURTH SEMESTER – APRIL 2006
ML 4805 – NON INVASIVE TECHNIQUES
(Also equivalent to ML 4801)
Date & Time : 20-04-2006/FORENOON Dept. No. Max. : 100 Marks
Part A (Answer All) 10 ´ 2 = 20
- Name the four types of electrode system.
- What is heart block? Mention its types.
- Define montage electrode selector.
- Name the two types of computed tomography.
- What are the four basic densities on an X ray and mention the colour which appears on the X ray film.
- Mention the interfering factors that occur while performing electroencephalography.
- What are the causes for hyperfluorescence and hypofluorescence.
- List the four MRI methods that are available for examination.
- Name the three tests that are performed in evoked potential studies.
- What are invasive and non-invasive techniques.
Part B (Answer any four) 4 ´ 10 = 40
- Write the principle and working mechanism of electroencephalography.
- Describe visual acuity in detail.
- Describe the principle of X ray. Mention its types and uses.
- Explain the principle of Doppler ultrasonography.
- Explain principle, procedure and limitations of MRI.
- Explain the principle and recording set up of electromyography.
Part C (Answer any two) 2 ´ 20 = 40
- Explain in detail the principle, procedure and recordings of ECG.
- Describe in detail the Transcranial Doppler studies.
- Explain positron emission tomography in detail.
- Explain the principle, procedure and working mechanism of computed tomography.
Loyola College M.Sc. Medical Lab Technology April 2006 Methodology Of Medical Laboratory Research Question Paper PDF Download
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LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
M.Sc. DEGREE EXAMINATION – MEDICAL LAB TECHNOLOGY
SECOND SEMESTER – APRIL 2006
ML 2951 – METHODOLOGY OF MEDICAL LABORATORY RESEARCH
Date & Time : 24-04-2006/9.00-12.00 Dept. No. Max. : 100 Marks
Part A (Answer All) 10 X 2 = 20
- Distinguish research methods from research methodology.
- What are the major objectives of research?
- What is the statement given by International covenant on civil and political rights in the year 1966?
- What is Helsinki declaration?
- What is intellectual property rights?
- Expand the abbreviations: STARD, ICMR, NRDMS,CSIR.
- Name the three ethical principles that govern research with human subjects.
- Distinguish acclimation from acclimatization.
- Mention any two thrust areas in medical research.
- What is scattered diagram?
Part B (Answer any four) 4 X 10 = 40
- Give an account on principles and methods of patenting.
- Describe the entire research process with a flow chart.
- Give an account on Nuremberg code.
- What are the components of an ethically valid informed consent for research?
- Write any ten research programs that are performed in India and abroad.
- Find out the correlation co-efficient in the following cases:
Age of human in days (x) | 5 | 10 | 15 | 20 | 25 | 30 | 35 |
Urea level (y) | 3 | 7 | 12 | 15 | 20 | 25 | 30 |
Determine “r” value.
Part C (Answer any two) 2 X 20 = 40
- Describe the format about preparation of manuscript for scientific publication.
- Write an assay on various types of literature to be surveyed in research.
- Explain in detail about the preparation of a research project proposal.
- On the basis of the following information, can it be concluded that Tobacco chewing and oral cancer are independent? ( at 5% level of significance the chi-square table value is 3.841 for one df.
Oral cancer | No oral cancer | |
Chewers | 75 | 105 |
Non Chewers | 25 | 95 |
Loyola College M.Sc. Medical Lab Technology April 2006 Medical Transcription Question Paper PDF Download
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
M.Sc. DEGREE EXAMINATION – MEDICAL LAB TECHNOLOGY
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FOURTH SEMESTER – APRIL 2006
ML 4900 – MEDICAL TRANSCRIPTION
Date & Time : 25-04-2006/9.00-12.00 Dept. No. Max. : 100 Marks
Part A (Answer All) 10 ´ 2 = 20
- Define two types of respiration.
- What are autoimmune diseases?
- What is fibrinolytics?
- Define Otitis media and Otitis externa.
- What are abbreviations in MT? Give two examples.
- Define aminocentesis.
- Define epilepsy and multiple sclerosis.
- What is a Transquilizer?
- Define diabetic retinopathy and glaucoma.
- Define cryosurgery and seizure disorder.
Part B (Answer any four) 4 ´ 10 = 40
- Describe two types of immunity in human body.
- Describe the transcription guidelines for: a) Abbreviations, b) Periods, c) Plurals and d) Acronyms.
- Describe the pathology of food in the gastrointestinal tract with a neat diagram.
- Write a short note on any three accessory organs of the skin in integumentary system.
- How will you transcribe voice message in medical transcription?
- Write a short note on functions of central nervous system and peripheral nervous system.
Part C (Answer any two) 2 ´ 20 = 40
- Draw a neat-labeled sketch of various parts of human eye. Add a note on any five of the lab procedure involved in ophthalmology.
- Explain the importance of parts of speech in MT.
- Write a note on pathology of pulmonary system with a neat diagram.
- Describe the laboratory procedure and pharmacological drugs involved in gynecology.
Loyola College M.Sc. Medical Lab Technology April 2006 Immunology Question Paper PDF Download
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
M.Sc. DEGREE EXAMINATION – MEDICAL LAB TECHNOLOGY
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SECOND SEMESTER – APRIL 2006
ML 2809 – IMMUNOLOGY
Date & Time : 21-04-2006/9.00-12.00 Dept. No. Max. : 100 Marks
Part A (Answer All) 10 X 2 = 20
- What is HLA?
- Explain clonal selection theory.
- Define the term “apoptosis”
- Comment on antigen presenting cell.
- Draw the structure of IgA.
- What is chemotactic reaction?
- Write the functions of CD4 and CD8.
- Explain the term “sensitization”.
- Write the principle of pregnancy test.
- List out the salient features of IL-1and IL-2.
Part B (Answer any four) 4 X 10 = 40
11. What is immunity ?Give an account of innative immunity with suitable examples.
- Describe in detail the structure and functions of secondary lymphoid organs.
13 Define cytokines.Write briefly various applications and types of interleukines.
- Discuss any two precipitation reaction.
- Write the mechanism of immunity against the viral infection.
- Give a detailed account of MHC molecules.
Part C (Answer any two) 2 X 20 = 40
- Discribe in detail the alternative and classical pathways of complement system.
- Write an essay on different types of vaccines and add a note on immunization schedule.
- Define hypersensitivity. Explain IgE mediated hypersensitivity reaction.
- Write a note on the principle and significance of immunoelectrophoresis and ELISA.
Loyola College M.Sc. Medical Lab Technology April 2006 Human Pathogens Question Paper PDF Download
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
M.Sc. DEGREE EXAMINATION – MEDICAL LAB TECHNOLOGY
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SECOND SEMESTER – APRIL 2006
ML 2801 – HUMAN PATHOGENS
Date & Time : 19-04-2006/FORENOON Dept. No. Max. : 100 Marks
Part A (Answer All) 10 ´ 2 = 20
- What are the general characteristics of spirochaetes and compare those characteristics with other bacteria.
- List the virulent factors of Staphylococcus aureus.
- Give two examples of primary cell culture and continuous culture.
- What are virions?
- Give the causative agents of coccidioidiomycosis, Blastomycosis
- What are dimatiaceous fungi?
- Differentiate amoebic and bacillary dysentery.
- What are the characteristics of a fertilized egg of Ascaris
- Mention any four DNA viruses
- Write the mode of infection, portal of entry, infecting agent and site of localization of Fasciolopsis buski.
Part B (Answer any four) 4 ´ 10 = 40
- Explain the circumstances and events leading to gas gangrene.
- Explain the action of Vibrio toxin and its pathogenesis.
- Discuss the four stages of disease caused by Rabies virus in humans.
- Enumerate the fungi causing chromomycosis. Add a note on its pathogenesis and clinical findings.
- Give a general account of intestinal flagellates.
- Write in detail about the life cycle of Ancylostoma duodenale.
Part C (Answer any two) 2 ´ 20 = 40
- Write an essay on the four major clinical syndromes of Salmonella.
- Explain the two types of life cycle exhibited by phages.
- Give a general account of Candida albicans.
- Explain in detail the life cycle of malarial parasite in man.
Loyola College M.Sc. Medical Lab Technology April 2006 Human Disorder Question Paper PDF Download
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
M.Sc. DEGREE EXAMINATION – MEDICAL LAB TECHNOLOGY
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FOURTH SEMESTER – APRIL 2006
ML 4950 – HUMAN DISORDER
Date & Time : 22-04-2006/9.00-12.00 Dept. No. Max. : 100 Marks
Part A (Answer All) 10 X 2 = 20
- What is gaucher’s disease?
- Write the importance of tyrosine.
- Comment on congenital heart disease.
- Differentiate acute and chronic ischaemia.
- List out the causes of diarrhea.
- Define gastritis.
- What is IOP ?
- What is prostate specific antigen?.
- Explain secretory otitis media.
- Write critical notes on conn’s syndrome.
Part B (Answer any four) 4 X 10 = 40
- Give an account of glycogen storage diseases.
- What is angina pectoris? Explain their types.
- Write a short notes on cataract and glaucoma.
- Describe in detail the characteristics of peptic ulcer.
- Explain different types of hepatitis.
- Give an account of phenylketonuria and alkaptonuria with their reactions.
Part C (Answer any two) 2 X 20 = 40
- Write an essay on effects of hypertension on human body.
- Give a detailed account on the features of stomach and colon cancers
- Describe in detail the structure and abnormalities of Adrenal gland
- Describe in detail the diseases related human ear.
Loyola College M.Sc. Medical Lab Technology April 2006 Human Anatomy & Physiology Question Paper PDF Download
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
M.Sc. DEGREE EXAMINATION – MEDICAL SOCIOLOGY
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SECOND SEMESTER – APRIL 2006
ML 2901 – HUMAN ANATOMY & PHYSIOLOGY
Date & Time : 28-04-2006/9.00-12.00 Dept. No. Max. : 100 Marks
Part A (Answer All) 10 ´ 2 = 20
- What are the different layers of human skin?
- Name the two types of sweat glands.
- What are gigantism and dwarfism?
- Define tidal volume and inspiratory reserve volume.
- What is cardiac cycle?
- Classify broadly the nervous system.
- Write the classification of muscles.
- What are the hormones secreted by the posterior lobes of pituitary gland.
- What are the secondary sexual organs in male?
- What is amniocentesis?
Part B (Answer any four) 4 ´ 10 = 40
- Give an account on gastric function test.
- Define autonomic nervous system. Write the differences between parasympathetic
and sympathetic nervous system.
- Give an account on respiratory organs.
- Explain the structure and functions of kidney.
- Give an account on the pancreatic hormones.
- Describe various methods of birth control.
Part C (Answer any two) 2 ´ 20 = 40
- Give an account on functions of various parts of central nervous system.
- Explain in detail the role of growth hormone and associated disorders.
- What is menstrual cycle? Explain the three phases involved in it.
- Give a detailed account on the hydrolytic enzymes in man.
Loyola College M.Sc. Medical Lab Technology April 2006 Advanced Lab. Techniques Question Paper PDF Download
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
M.Sc. DEGREE EXAMINATION – MEDICAL LAB TECHNOLOGY
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SECOND SEMESTER – APRIL 2006
ML 2952 – ADVANCED LAB. TECHNIQUES
Date & Time : 24-04-2006/9.00-12.00 Dept. No. Max. : 100 Marks
Part A (Answer All) 10 ´ 2 = 20
- List out any four protein transfer procedure.
- What is ponceou S and PVDF?
- What are ramification amplification?
- Write the goals of HGP.
- Define gene therapy.
- Define obligatory paternal gene.
- What is direct exclusion?
- Define Two haplotype exclusion
- What is parentage testing?
- Expand the abbreviations: SWGDAM, FBI, CODIS, NDIS.
Part B (Answer any four) 4 ´ 10 = 40
- Write a short note on DNA polymorphism.
- Describe in brief human leukocyte antigen.
- Comment on documentation and reporting parentage-testing results.
- Describe in detail any two gene sequencing method.
- Give an account on human genome project.
- Describe in detail the micro array procedure and add a note on its clinical application.
Part C (Answer any two) 2 ´ 20 = 40
- Explain in detail the DNA testing method.
- Describe molecular techniques in the diagnosis of hematopoitic neoplasm.
- Write the importance of molecular techniques used in the diagnosis of leukemia.
- Discuss the techniques to detect antigen receptor gene rearrangement.
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Loyola College M.Sc. Medical Lab Technology Nov 2006 Statistical Applications In Biological Sciences Question Paper PDF Download
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
M.Sc. DEGREE EXAMINATION – BIOMED.INSTR.&MED.LABO.TECHNO.
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THIRD SEMESTER – NOV 2006
ST 3901 – STATISTICAL APPLICATIONS IN BIOLOGICAL SCIENCES
Date & Time : 03-11-2006/9.00-12.00 Dept. No. Max. : 100 Marks
Part A
Answer all the questions. 10 X 2 = 20
- Define statistics.
- What are the advantages of diagrammatic presentation of data?
- State the various measures of central tendency.
- Define dispersion.
- What do you understand by skewness and kurtosis?
- Explain the meaning and significance of the concept of correlation.
- Define statistic and parameter.
- What is type II error?
- Write any two uses of chi-square test.
- What is analysis of variance?
PART -B
Answer any five questions. 5 X 8 = 40
- Briefly explain the scope, limitation and misuse of statistics.
- The following data relate to the monthly expenditure ( in rupees) of the families A and B:
Items of expenditure Family A Family B
Food 1600 1200
Clothing 800 600
Rent 600 500
Light and Fuel 200 100
Miscellaneous 800 600
Represent the above data by a suitable percentage diagram.
- Calculate mean, median and standard deviation for the following data:
Age : 10-20 20-30 30-40 40-50 50-60 60-70
No. of death by HIV: 2 6 10 7 4 1
14. Calculate Spearman’s coefficient of correlation between height and weight are given below:
Age : 2 5 8 10 12 18 20 25
Weight: 4 8 15 28 32 45 50 60
- In a random sample of 1000 persons from city Trichy, 400 are found to be consumers of Hans. In a sample of 800 from city Tanjore , 400 are found to be consumers of tobacco. Do these data reveal a significant difference between city Trichy and Tanjore, so far as the proportion of tobacco is concerned?
- The following table shows the ages (X) and blood pressure (Y) of 8 persons.
X: 52 63 45 36 72 65 47 25
Y: 62 53 51 25 79 43 60 33
Obtain the regression equation of Y on X and find the expected blood pressure fo a person who is 49 years old.
- 500 apples are taken at random from a large basket and 50 are found to be bad. Estimate the proportion of bad apples in the basket and assign limits within which the percentage most probably lies.
- From the following table find is there any significance difference between treatments or not.
Treatment | Treatment1 | Treatment2 | Treatment3 | Treatment4 |
Kumar
Senthil Saravanan |
80
70 68 |
100
88 99 |
110
96 79 |
70
85 94 |
PART C
Answer any two questions. 2 X 20 = 40
- Explain different types of diagrams in statistics with an illustration.
- For a random sample of 10 persons, fed on diet A, the increased weight in pounds in a certain period were:
10 6 16 17 13 12 8 14 15 9
For another random sample of 12 persons, fed on diet B, the increase in same period were:
7 13 22 15 12 14 18 8 21 23 10 17
Test whether the diets A and B differ significantly as regards their effect on increase in weight.
Given the following data:
Degrees of freedom : 19 20 21 22 23
Values of t at 5 % level: 2.09 2.09 2.08 2.07 2.07
- a). A certain drug is claimed to be effective in curing cold. In an experiment on 1000 persons with cold, out of which 250 were given the drug and 250 were given sugar pills. The patients reactions to the treatment are recorded in the following table:
Medicine helped harmed no effect total
Drug 150 30 70 250
Sugar pills 130 40 80 250
On the basis of the data can it be concluded that there is a significant difference in
the effect of the drug and sugar pills?
b). The average life span of people in Trichy district is 65 years with the
standard deviation of 4 years. Randomly 10 people were observed and their life
span were recorded:
45 60 75 72 68 63 65 68 70 71
Verify that is there any significance at 5 % level of signifance.
- Four students were selected randomly from II M.Sc medical lab technology and they were given by different types of medicine for curing viral fever. The following hours have been taken by the medicine to cure the diseases.
Student medicine1 medicine2 medicine3 medicine4
Senthil 0.30 0.35 0.40 0.45
Ishwariya 0.50 0.55 0.46 0.48
Kannan 0.10 0.20 0.25 0.29
Sona 0.50 0.40 0.45 0.30
Is there any significance difference between medicines and students for taking
hours to cure the disease?
Loyola College M.Sc. Medical Lab Technology Nov 2006 Pharmaceutical Chemistry And Toxicology Question Paper PDF Download
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
M.Sc. DEGREE EXAMINATION – MEDICAL LAB. TECHNOLOGY
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THIRD SEMESTER – NOV 2006
ML 3875 – PHARMACEUTICAL CHEMISTRY AND TOXICOLOGY
Date & Time : 06-11-2006/9.00-12.00 Dept. No. Max. : 100 Marks
PART A
Answer all the questions (10×2=20 Marks)
- Give the difference between ‘invivo’ and ‘invitro’ analysis of drugs.
- Explain the terms : a) Pharmacology b) Pharmacophore c) Pharmacokinetics
- d) Pharmacodynamics
- What are the different isotopes of carbon? How is it useful in medicinal field?
- What is meant by ‘cut off point’? Give an example.
- What is meant by ‘Buffer’? Mention its significance in designing drugs.
- What are the four basic types of chemical interactions?
- Define Lamellae & Liminent.
8.What is meant by first pass biotransformation.
9.Define FAS.
- What is meant by Intraosseous route of administration?
PART B
Answer any four of the following: (4×10=40 Marks)
- Explain briefly with examples
- a) Preservatives b) Ointment bases c) Colouring and sweetening agent in drugs.
- Explain the relationship between the chemcal structure and pharmacological activity
using alkyl and acidic groups in drugs.
- Discuss the importance of chelation in explaining the biological activity of
compounds.
- Discuss the factors influencing Toxicity.
- Explain the different methods of administering drugs.
- What are the applications of radioisotopes in biological sciences.
PART C
Answer any two of the following: (2×20=40 Marks)
- a) Explain the classification of drugs with examples
- b) How is radioactivity measured by Geiger – Muller counters
- Enumerate the physiochemical constants for prediction of bio activities.
19.Classify teratogens and write short notes on
- Fetal alcohol Syndrome b)Phenytoin c)Thalidomide
- Explain the process of drug absorption.
Loyola College M.Sc. Medical Lab Technology Nov 2006 Molecular Biology Question Paper PDF Download
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
M.Sc. DEGREE EXAMINATION – MEDICAL LAB. TECHNOLOGY
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FIRST SEMESTER – NOV 2006
ML 1809 – MOLECULAR BIOLOGY
Date & Time : 31-10-2006/1.00-4.00 Dept. No. Max. : 100 Marks
SECTION-A
Answer all the questions 2X10=20marks
- Mention the role of topoisomerases?
- Draw the secondary structure of t-RNA
- What is Chargaff’s rule?
- Write notes on a) heterochromatin b) euchromatin
- List the different kinds of lysosomes and their functions
- What is RNA polymerase holoenzyme?
- What is photoreactivation repair mechanism?
- Expand the abbreviations
- a) APC b) CDKS
- What is the role of tyrosine kinases in cancer?
- What is Turner’s syndrome?
SECTION-B
Answer any four of the following 4X10=40marks
- Explain the special constraints relevant to genetic testing
- Explain the molecular structure of double stranded DNA.
- Describe the mechanism of transcription in eukaryotes.
- What are leading and lagging strands? List out the enzymes of DNA replication and their functions.
- Write a short note on viral oncogene.
- Give an account of on excision and recombination repair mechanisms.
SECTION-C
Answer any two of the following 2X20=40marks.
- Draw the eukaryotic cell and write notes on a) endoplasmic reticulum.
- b) golgi complex c) mitochondria.
- Explain in detail the process of protein synthesis in prokaryotes.
- Describe in detail the regulation of eukaryotic cell cycle.
- Explain in detail the active transport of materials across plasma membrane.
Loyola College M.Sc. Medical Lab Technology Nov 2006 Medical Transcription Question Paper PDF Download
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034 M.Sc. DEGREE EXAMINATION – MEDICAL LAB. TECHNOLOGY
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FIRST SEMESTER – NOV 2006
ML 1952 – MEDICAL TRANSCRIPTION
Date & Time : 02-11-2006/1.00-4.00 Dept. No. Max. : 100 Marks
SECTION-A
Answer all the questions 2X10=20 marks
- What is Ectopic pregnancy?
- What is amniocentesis?
- List any six useful reference resources for MT.
- What is Osteoporosis?
- What is fracture? Write any two types.
- What is abbreviation?
- What is operative report?
- Write the functions of testosterone?
- What is cataract?
- Differentiate plasma from serum.
SECTION-B
Answer any four of the following 4X10=40 marks
- Describe and draw a labeled diagram of skeletal system.
- Discuss briefly the basic rules for formation of medical words.
- Give an account on anatomy and physiology of gastroenterology.
- Describe and draw a neat diagram of human eye.
- Write a short note on any two glands involved in endocrine system.
- Write a short note on steps involved in medical transcription.
SECTION –C
Answer any two of the following 2X20=40 marks.
- Write short notes on any four:
- History and physical formatting
- Discharge summary
- Consultation
- Operative
- Chart note
- Radiology report
- Describe the structure and functions of male genitalia.
- Discuss parts of speeches with reference to medical transcription.
- Discuss the importance of medical terminology in MT.
Loyola College M.Sc. Medical Lab Technology Nov 2006 Human Physiology Question Paper PDF Download
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034 M.Sc. DEGREE EXAMINATION – MEDICAL LAB. TECHNOLOGY
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THIRD SEMESTER – NOV 2006
ML 3801 – HUMAN PHYSIOLOGY
Date & Time : 27-10-2006/9.00-12.00 Dept. No. Max. : 100 Marks
SECTION-A
Answer all the questions 2X10=20marks
- List the three types of human hair & their functions.
- What is sebum? How is it secreted?
- Draw the structure of a human tooth & write the dental formula with expansion.
- Define residual volume and functional residual capacity.
- What are the layers of epidermis?
- What is chloride shift?
- List the hormones that stimulate spermatogenesis & its functions.
- What is sinoatrial node?
- What is feed back mechanism in hormone secretion? Give an example.
- List a few differences between arteries & veins.
SECTION-B
Answer any four of the following 4X10=40marks
- Explain the mode of absorption of electrolytes and water in digestive system.
- Describe the birth control methods in detail.
- Explain in detail the process of micturition.
- Draw and explain the structure of lungs.
- Explain the different phases of gastric secretion.
- Explain the mechanism of muscle contraction.
SECTION –C
Answer any two of the following 2X20=40marks.
- What are gonadotropins? Explain their role in reproduction.
- Explain the role played by digestive enzymes in detail.
- Draw the structure of nephron and explain the mechanism of urine formation.
- Draw the structure of integumentary system. Explain a) Glands b)hair follicles.
Loyola College M.Sc. Medical Lab Technology Nov 2006 Hospital Management Question Paper PDF Download
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
M.Sc. DEGREE EXAMINATION – MEDICAL LAB. TECHNOLOGY
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FIRST SEMESTER – NOV 2006
ML 1951 – HOSPITAL MANAGEMENT
Date & Time : 02-11-2006/1.00-4.00 Dept. No. Max. : 100 Marks
PART A
Answer all the questions (2×10=20 Marks)
- What are the objectives of out -patient service department?
- List the records to be maintained in casualty and emergency departments.
- What is the need for Human Resource Development?
- What are the functions of Materials Management Department?
- Define Inventory.
- What is a balance sheet?
- What are the two systems of book keeping?
- Define a medical record.
- What is meant by “public” in relation to hospital environment?
- What are the factors involved in Good ward management?
PART B
Answer any four of the following: (10×4=40 Marks)
- What is the role of an Administrator in Hospital environment? Explain.
- Explain the European Model of Operation Theatre.
- Define Job Satisfaction. Explain its consequences.
- Explain in detail the principles involved in Material Handling.
- What is a ware house? What are its functions?
16.What is quality assurance? Discuss the role of quality management in a hospital.
PART C
Answer any two of the following: (20×2=20 Marks)
17. Explain the process and techniques of Performance Appraisal System.
18. What do you mean by ABC analysis? Explain its utility in Inventory Management.
- Discuss the purpose, function and importance of Medical Records.
- Write an essay on Hospital Waste Management.