Ayush

HINGU

Hingu consists of oleo-gum-resin obtained from rhizomes and roots of Ferula foetida Regel., Ferula narthex Bioss,and other species of Ferula (Fam. Umbelliferm), a perennial herb, occurring in Persia and Afghanistan, resin collected after making incisions at the upper part of tap root of more than five year old plants by scrapping in March, April, just before flowering, whole process repeated many times, after one or two days or after a few weeks when it gets hardened.

SYNONYMS

Sanskrit : Ramaha, Sahasravedhi
Assamese : Hin
Bengali : Hing
English : Asfoetida
Gujrati : Hing, Vagharni
Hindi : Hing, Hingda
Kannada : Hing, Ingu
Kashmiri : Eng
Malayalam : Kayam
Marathi : Hing, Hira, Hing
Oriya : Hengu, Hingu
Punjabi : Hing
Tamil : Perungayam
Telugu : Inguva
Urdu : Hitleet, Hing

DESCRIPTION

a) Macroscopic

Rounded, flattened or masses of agglutinated tears, greyish-white to dull yellow, mostly 12-25 mm in diameter, freshly exposed surface, yellowish and translucent or milky white, opaque, slowly becoming pink, red, finally reddish brown, odour, strong, characteristic and persistent, taste, bitter and acrid.

IDENTITY, PURITY AND STRENGTH

Identification

(I) Freshly broken surface when touched with sulphuric acid a bright red or reddishbrown colour is produced, changing to violet when acid washed off with water.
(II) Boil 0.2 g with 2 ml Hydrochloric acid for about 1 minute, cool, dilute with an equal volume of water, and filter into 3 ml of dilute solution of Ammonia, fluorescence is produced.

Absence of colophony resin:-Triturate 1 g with 10 ml of Light Petroleum (b.p. 40o-60o) for 2 minutes, filter into a test tube and add to the filtrate 10 ml of a fresh 0.5 per cent w/v aqueous solution of copper acetate, shake well and allow the liquids to separate, petroleum layer does not show any green colour, indicating absence of colophony resin.

IDENTITY, PURITY AND STRENGTH

Foreign matter Not more than 2 per cent, Appendix 2.2.2.
Total Ash Not more than 15 per cent, Appendix 2.2.3.
Acid-insoluble ash Not more than 3 per cent, Appendix 2.2.4.
Alcohol-soluble extractive Not less than 50 per cent, Appendix 2.2.6.
Water-soluble extractive Not less than 50 per cent, Appendix 2.2.7.

ASSAY

Place about 5 g accurately weighed, in a small beaker furnished with a glass rod, and tared add 50 ml of Alcohol (90 per cent), and boil gently. Filter the hot solution through a tared filter paper and boil the residue with further quantities of Alcohol (90 per cent); unitl all soluble matter is removed, using the glass rod to disintegrate the soluble matter. Wash the filter paper with hot alcohol (90 per cent) transfer the paper to the beaker, dry the 100o, and weigh. The- residue weighs not more than 50 per cent of the original sample taken.

CONSTITUENTS – Essential oil, gum and resin.

PROPERTIES AND ACTION

Rasa : Katu
Guna : Tiksna
Virya : Usna
Vipaka : Katu
Karma : Anulomana, Dipana, Hrdya, Krmighna, Pacana, Rucya, Vatakaphaprasamana

IMPORTANT FORMULATIONS – Hingvastaka Curna, Hingvadi Curna, Hinguvacadu Curna

THERAPEUTIC USES – Sularoga, Adhmana, Gulma, Hrdroga, Krmiroga, Udararoga, Agnimandya, Anaha

DOSE – 125-500 mg of the drug.

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GUGGULU

Guggulu consists of exudate of Commiphora wightii (Arn.) Bhand, Syn. Balsamodendron mukul Hook. ex Stocks Commiphora mukul Engl.), {Fam. Burseracem), a small perennial tree or shrub upto 1.2-1.8 m high, occuring in rocky tracts of Rajasthan, Gujarat , exudate is collected during winter season by making the incisions in the bark or in summer, falling from the bark itself.

SYNONYMS

Sanskrit : Pura, Mahisaksa, Kausika, Palankasa
Assamese : Guggul
Bengali : Guggula
English : Gum-gugul, Indian Bdellium
Gujrati : Gugal, Guggal, Gugar
Hindi : Guggul
Kannada : Kanthagana, Guggala, Mahishaksha guggulu, Guggulugida, Guggulu
Guggal
Kashmiri : Guggul Dhoop, Kanth Gan
Malayalam : Gulgulu, Guggulu
Marathi : Guggul, Mahishaksh
Oriya : Guggulu
Punjabi : Guggal
Tamil : Mahisaksi Guggalu
Telugu : Makishakshi guggulu, Guggipannu
Urdu : Muqil (Shihappu)

DESCRIPTION

a) Macroscopic

Drug occurs in vermicular or stalactitic pieces of pale yellow or brown coloured mass, makes milky emulsion in hot water and readily burns, when fresh viscid and golden coloured, odour, aromtic, taste., bitter and astringent.

b) Microscopic

IDENTITY, PURITY AND STRENGTH

Foreign matter Not more than 4 per cent, Appendix 2.2.2.
Total Ash Not more than 5 per cent, Appendix 2.2.3.
Acid-insoluble ash Not more than 1 per cent, Appendix 2.2.4.
Alcohol-soluble extractive Not less than 27 per cent, Appendix 2.2.6.
Water-soluble extractive Not less than 53 per cent, Appendix 2.2.7.
Volatile oil Not less than 1 per cent, Appendix 2.2.10

CONSTITUENTS – Essential oil, gum, resin, steroids.

PROPERTIES AND ACTION

Rasa : Katu, Tikta, Kasaya
Guna : Laghu, Sara, Vasada
Virya : Usna
Vipaka : Katu
Karma : Balya, Rasayana, Varnya, Vatabalasajit, Bhagnasandhanakrt, Medohara

IMPORTANT FORMULATIONS – Vatari Guggulu, Yogaraja Guggulu, Simhanada Guggulu, Kaisora Guggulu, Mahayogaraja Guggulu, Candraprabha Vati

THERAPEUTIC USES – Amavata, Kustha, Prameha, Vatavyadi, Granthi, Sopha, Gandamala, Medoroga

DOSE – 2-4 g of the drug.

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JATAMAMSI

Jatamamsi consists of dried rhizome of Nardostachys jatamansi DC.(Fam. Valerianacem) , an errect perennial herb, 10-60 cm high growing at an altitude of 3000-5000 m on the sub-alpine Himalayan tracts.

SYNONYMS

Sanskrit : Mamsi, Jaa, Jaila
Assamese : Jatamansi, Jatamangshi
Bengali : Jatamamsi
English : Nardus root
Gujrati : Baalchad, Kalichad
Hindi : Balchara
Kannada : Bhootajata, Ganagila maste
Kashmiri : Bhutijata
Malayalam : Manchi, Jatamanchi
Marathi : Jatamansi
Oriya : Jatamansi
Punjabi : Billilotan, Balchhar, Chharguddi
Tamil : Jatamanji
Telugu : Jatamams
Urdu : Sumbul-ut-teeb

DESCRIPTION

a) Macroscopic

Dried rhizome dark brown, 2.5-7.5 cm long, cylindrical, covered with reddishbrown fibres forming a net work, which are skeletons of sheathing leaf bases, fracture, brittle, internal colour reddish-brown, colour, strongly aromatic, taste, acrid, slightly bitter.

b) Microscopic

Transverse section of rhizome shows cork consisting of 2-5 layers of cells filled with oil globules, cortex characterised by the presence of schizogenous canals, phloem in form of patches of small cells, cambium ring distinct and continuous, xylem consists of vessles, scattered individually or in rows of two or three vessels, with scalariform thickening, older rhizomes show one or more stellate shaped rings of interxylary and medullary cork, completely or incompletely separating the rhizome into four to nine vascular strands by joining outer cork, each separated strand encircled by a few layers of cork cell consisting of an outer cortex zone followed by two or more functional vascular bundles, tissues in between the strands usually non-functional except for the cork cells which act as storage organ for oil globule.

IDENTITY, PURITY AND STRENGTH

Identification-

Shake about 2 g of the powder with 5 ml of Alcohol (80 per cent) for ten minutes and filter, Place one drop of the filtrate on a filter paper, dry and examine under ultra-violet light, a bright, bluish-white fluorescene is visible.

IDENTITY, PURITY AND STRENGTH

Foreign matter Not more than 5 per cent, Appendix 2.2.2.
Total Ash Not more than 9 per cent, Appendix 2.2.3.
Acid-insoluble ash Not more than 5 per cent, Appendix 2.2.4.
Alcohol-soluble extractive Not less than 2 per cent, Appendix 2.2.6.
Water-soluble extractive Not less than 5 per cent, Appendix 2.2.7.
Volatile oil Not less than 0.1 per cent, Appendix 2.2.10

CONSTITUENTS – Essential oil and resinuous matter.

PROPERTIES AND ACTION

Rasa : Tikta, Kasaya
Guna : Laghu
Virya : Sita
Vipaka : Katu
Karma : Medhya, Tridosanut, Varnya, Nidrajanana, Kushaghna.

IMPORTANT FORMULATIONS – Jatamamsyarka

THERAPEUTIC USES – Daha, Kustha, Visarpa, Manasaroga, Anidra

DOSE – 2-3 g of the drug in powder form.
5-10 g of the drug for decoction.

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GUDUCI

Guduci consists of dried, matured pieces of stem of Tinospora cordifolia (Willd.) Miers. (Fam, Menispermacem), a perennial climber found throughout Tropical India, drug collected during summer preferably in the month of May, drug is used in fresh form also.

SYNONYMS

Sanskrit : Amrtavalli, Amrta, Madhuparni, Guducika, Chinnobhava
Assamese : Siddhilata, Amarlata
Bengali : Gulancha
English : —
Gujrati : Galac, Garo
Hindi : Giloe, Gurcha
Kannada : Amrutaballi
Kashmiri : Amrita, Gilo
Malayalam : Chittamrutu
Marathi : Gulvel
Oriya : Guluchi
Punjabi : Gilo
Tamil : Seendal, Seendil kodi
Telugu : Thippateega
Urdu : Gilo

DESCRIPTION

a) Macroscopic

Drug occurs in pieces of varying thickness ranging from 0.6-5 cm in diameter, young stems green with smooth surfaces and swelling at nodes, older ones show a light brown surface marked with warty protuberances due to circular lenticels, transversely smoothened surface shows a radial structure with conspicuous medullary rays traversing porous tissues, taste bitter.

b) Microscopic

Transverse section of stem shows outer-most layer of cork, differentiating into outer zone of thick-walled brownish and compressed cells, inner zone of thin walled colourless, tangentially arranged 3-4 rows of cells, cork broken at some places due to opening of lenticels, followed by 5 or more rows of secondary cortex of which the cells of outer rows smaller than the inner one, just within the opening of lenticels, groups of sclereids consisting of 2-10 cells found in secondary cortex region, outer zone of cortex consists of 3–5 rows of irregularly arranged, tangentially elongated chlorenchymatous cells, cortical cells situated towards inner side, polygonal in shape and filled with plenty of starch grains, simple, ovoid, or irregularly ovoid-elliptical, occasionally compound of 2-4 components, several secretory cells, found scattered in the cortex, pericyclic fibres lignified with wide lumen and pointed ends, associated with a large number of crystal fibres containing a single prism in each chamber, vascular zone composed of 10-12 or more wedge-shaped strips of xylem, externally surrounded by semi-circular strips of phloem, alternating, with wide medullary rays, phloem consists of sieve tube, companion cells and phloem parenchyma of polygonal or tangentially elongated cells, some of them contain cryste1s of calcium oxalate, cambium composed of one to two layers of tangentially elongated cells in each vascular bundle, xylem consists of vessels, tracheids, parenchyma and fibres, in primary xylem, vessels comparatively narrow devoid of tyloses, secondary xylem elements thick-walled, lignified, vessels cylindrical in shape bearing bordered pits on their walls some large vessels possess several tyloses and often contain transverse septa, meduallry rays 15-20 or more cells wide containing rounded, hemispherical, oblong, ovoid, with faintly marked concentric striations and central hilum appearing like a point, starch grains of 5.5-11.20 μ in diameter and 6-11.28 μ in length, pith composed of large, thin-walled cells mostly containing starch grains.

IDENTITY, PURITY AND STRENGTH

For dried drug –
Foreign matter Not more than 2 per cent, Appendix 2.2.2.
Total ash Not more than 16 per cent, Appendix 2.2.3.
Acid-insoluble ash Not more than 3 per cent, Appendix 2.2.4.
Alcohol-soluble extractive Not less than 3 per cent, Appendix 2.2.6.
Water-soluble extractive Not less than 11 per cent, Appendix 2.2.7
For fresh drug
Foreign matter Nil Appendix 2.2.2.
Moisture content 75 per cent, Appendix 2.2.9.

CONSTITUENTS – Terpenoids and alkaloids.

PROPERTIES AND ACTION

Rasa : Tikta, Kasaya
Guna : Laghu
Virya : Usna
Vipaka : Madhura
Karma : Balya, Dipana, Rasayana, Sangrahi, Tridosasamaka, Raktasodhaka, Jvaraghna

IMPORTANT FORMULATIONS – Amrtarisa, Amrtottara Kvatha Curna, Guduci Taila, Guducyadi Curna, Guduci Sattva, Chinnobhavadi Kvatha Curna

THERAPEUTIC USES – Jvara, Kustha, Pandu, Prameha, Vatarakta, Kamala

DOSE – 3-6 g of the drug in powder form.
20-30 g of the drug for decoction.

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JATIPHALA

Jatiphala consists of the endosperm of dried seeds (kernels of fruits) of Myristica fragrans Houtt. (Fam. Myristicacem), dioecious or occasionally monoecious aromatic tree, about 10-20 m high, found mostly in Tamil Nadu and to some extent in Kerala, Andhra Pradesh and Assam.

SYNONYMS

Sanskrit : Jatisasya, Jatiphala
Assamese : Jaiphal, Kanivish
Bengali : Jaiphala, Jaitri
English : Nutmeg
Gujrati : Jaiphala, Jayfar
Hindi : Jaiphal
Kannada : Jadikai, Jaykai, Jaidikai
Kashmiri : Jafal
Malayalam : Jatika
Marathi : Jaiphal
Oriya : Jaiphal
Punjabi : Jaiphal
Tamil : Sathikkai, Jathikkai, Jatikkai, Jadhikai, Jadhikkai
Telugu : Jajikaya
Urdu : Jauzbuwa, Jaiphal

DESCRIPTION

a) Macroscopic

Seed ellipsoid, 20-30 mm long and about 20 mm broad, externally greenishbrown sometimes marked with small irregular dark brown patches or minute dark points and lines slightly furrowed reticulately, a small light-coloured area at one end indicating the position of the radicle a groove running along the line of raphe to the darker chalaza at the opposite end, surrounded by a thin layer of peri sperm with infoldings appearing as dark ruminations in the abundant greyish-brown endosperm, embryo, in an irregular cavity, small with two widely spreading crumpled cotyledons and a small radicle odour, strong and aromatic, taste, pungent and aromatic.

b) Microscopic

Transverse section of endosperm shows peripheral perisperm, of several layers of strongly, flattened polyhederal cells with brown contents, or containing prismatic crystals, inner layer of perisperm of thin-walled parenchyma about 40 n thick, infolding into the tissue of the endosperm to form the ruminations containing numerous, very largeoil cells with brown cell walls, vascular strands, in the peripheral region, numerous small spiral vessels, large celled, endosperm, parenchymatous With occasional tannin idioblasts with thin brown walls, containing numerous simple, rounded and compound starch grains, with upto about 10 components usually 2-8 individual grains, upto 20 n in diameter present, most of the cells with crystalline fat and often a large aleurone grain in each cell, containing a rhombic protein crystal upto 12 n and small aleurone grains with less regular crystalloids, embryo, of shrivelled and collapsed parenchyma.

IDENTITY, PURITY AND STRENGTH

Foreign matter Not more than 1 per cent, Appendix 2.2.2.
Total Ash Not more than 3 per cent, Appendix 2.2.3.
Acid-insoluble ash Not more than 0.5 per cent, Appendix 2.2.4.
Alcohol-soluble extractive Not less than 11 per cent, Appendix 2.2.6.
Water-soluble extractive Not less than 7 per cent, Appendix 2.2.7.
Ether soluble extractive Not less than 25 per cent, Appendix 2.2.8
Volatile oil Not less than 5 per cent, Appendix 2.2.10

CONSTITUENTS – Essential oil and fixed oil.

PROPERTIES AND ACTION

Rasa : Katu, Tikta
Guna : Laghu, Tiksna
Virya : Usna
Vipaka : Katu
Karma : Dipana, Grahi, Vrsya, Mukhakledanasaka, Mukhadaurgandhyanasaka, Kaphavatapana

IMPORTANT FORMULATIONS – Jatiphaladi Curna

THERAPEUTIC USES – Atisara, Svasa, Chardi, Kasa, Pinasa, Grahani, Mukharoga, Sukrameha

DOSE – 0.5 – 1.0 g of the drug in powder form.

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GOKSURA (Fruit)

Goksura consists of dried, ripe, entire fruit of Tribulus terrestris Linn. (Fam Zygopyllaceae), an annual, rarely pernnial common weed of the pasture lands, road sides and other waste places, chiefly in hot, dry and sandy regions, grows throughout India as prostrate herb and upto 3,000 m in Kashmir.

SYNONYMS

Sanskrit : Svadamstra, Goksuraka, Traikantaka, Trikatna
Assamese : Gokhurkata, Gokshura
Bengali : Gokhri, Gokshura
English : Caltrops fruit
Gujrati : Bethagokharu, Mithagokhru, Nanagokharu
Hindi : Gokhru
Kannada : Neggilamullu, Neggilu, Sannaneggilu
Kashmiri : Pakhda, Michikand
Malayalam : Nerinjil
Marathi : Gokharu, Sarate
Oriya : Gokhyura, Gukhura
Punjabi : Bhakhra, Gokhru
Tamil : Nerinjil, Nerunjil
Telugu : Palleru Kaya
Urdu : Khar-e-Khasak Khurd

DESCRIPTION

a) Macroscopic

Fruit stalked, light or greenish yellow, five ribbed or angled, more or less spherical in structure and covered with short stiff or pubescent hairs, 1 cm in diameter with five pairs, of prominent short stiff spines, pointed downwards, about 0.5 cm in length, tips of spines almost meet in pairs whole together forming pentagonal framework around fruit, ripe fruit separates into five segment, of each cocci and each appears as single-fruit, each coccus semi-lunar or plano-convex in structure one chambered, armed with a pair of spines, starting from its middle, containing four or more seeds, taste, slightly astringent.

b) Microscopic

Transverse section of fruit shows small epidermal cells of each coccus rectangular, unicellular trichomes in abundance, mesocarp 6-10 layers of large parenchymatous cells, rosette of calcium oxalate crystals abundantly present, mesocarp followed by 3-4 compact layers of small cells containing prismatic crystals of calcium oxalate.

IDENTITY, PURITY AND STRENGTH

Foreign matter Not more than 1 per cent, Appendix 2.2.2.
Total Ash Not more than 15 per cent, Appendix 2.2.3.
Acid-insoluble ash Not more than 2 per cent, Appendix 2.2.4.
Alcohol-soluble extractive Not less than 6 per cent, Appendix 2.2.6.
Water-soluble extractive Not less than 10 per cent, Appendix 2.2.7.

CONSTITUENTS – Potassium nitrate, sterols, sapogenin with pyroketone ring (diosgenin), gitogenin and hecogenins.

PROPERTIES AND ACTION

Rasa : Madhura
Guna : Guru, Snigdha
Virya : Sita
Vipaka : Madhura
Karma : Brmhana, Vatanut, Vrsya, Asmarihara, Vastisodhana

IMPORTANT FORMULATIONS – Goksuradi Guggulu, Traikanaka Ghrta, Draksadi Cruna

THERAPEUTIC USES – Sularoga, Arsa, Svasa, Daurbalya, Hrdroga, Kasa, Mutrakrcchra, Asmari, Prameha

DOSE – 3-6 g of the drug in powder form.
20-30 g of the drug for decoction.

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KAMPILLA

Kampilla consists of glands and hairs of fruit of Mallotus philippinensis Muell . Arg. (Fam. Euphorbiacem), a very common perennial shrub or small tree found in outer Himalayas ascending to 1500 m, mature fruits collected in February-March, reddish brown powder collected in cloth by shaking and rubbing the fruits with hands.

SYNONYMS

Sanskrit : Rajanaka, Kampillaka
Assamese : Lochan
Bengali : Kamlagudi
English : Kamala
Gujrati : Kapilo
Hindi : Kabila
Kannada : Kapila, Chandrahettu, Kapilathettu
Kashmiri : Kameelak
Malayalam : Kampippala, Kampipalu
Marathi : Shendri, Kapila
Oriya : Kamalagundi
Punjabi : Kamila
Tamil : Kamala, Kampila
Telugu : Kampillamu
Urdu : Kamila

DESCRIPTION

a) Macroscopic

Fine, granular powder, dull-red or madder-red coloured, floating on water.

b) Microscopic

Under microscope glands appear depressed and globular, containing deep-red coloured resin, secreted by many club shaped cell radiating from a common centre, a number of stellate trichomes present, trichomes thick-walled, branching lignified with smooth margins, yellow coloured, arranged in small radiating groups.

IDENTITY, PURITY AND STRENGTH

Foreign matter Not more than 2 per cent, Appendix 2.2.2.
Total Ash Not more than 6 per cent, Appendix 2.2.3.
Acid-insoluble ash Not more than 4 per cent, Appendix 2.2.4.
Alcohol-soluble extractive Not less than 50 per cent, Appendix 2.2.6.
Water-soluble extractive Not less than 1.0 per cent, Appendix 2.2.7.

CONSTITUENTS – Resinous colouring matter (rottlerin).

PROPERTIES AND ACTION

Rasa : Katu
Guna : Laghu, Ruksa, Tiksna
Virya : Usna
Vipaka : Katu
Karma : Krmighna, Vranapaha, Virecana

IMPORTANT FORMULATIONS – Dhanvantara Ghrta, Misraka Sneha.

THERAPEUTIC USES – Adhmana, Gulma, Krmiroga, Vibandha, Vrana

DOSE – 0.5-1.0 g of the drug in powder form.

Note– Sodhana of this drug is to be done before use, as described in Appendix.

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GOKSURA (Root)

Goksura consists of root of Tribulus terrestris Linn. (Fam. Zygophyllacease): an annual prostrate herb, rarely perennial common weed of the pasture lands, road sides and other waste land, chiefly growing in hot, dry and sandy regions throughout India and upto 3,000 m in Kashmir.

SYNONYMS

Sanskrit : Goksuraka, Trikatna, Svadamstra, Traikantaka
Assamese : Gokshura, Gukhurkata
Bengali : Gokshura, Gokhri
English : Caltrops root
Gujrati : Be tha gokharu, Nana gokharu, Mithogokharu
Hindi : Gokhru
Kannada : Sannanaggilu, Neggilamullu, Neggilu
Kashmiri : Michirkand, Pakhda
Malayalam : Nerinjil
Marathi : Sarate, Gokharu
Oriya : Gukhura, Gokhyura
Punjabi : Bhakhra, Gokhru
Tamil : Nerinjil, Nerunjil
Telugu : Palleruveru
Urdu : Khar-e-Khasak Khurd

DESCRIPTION

a) Macroscopic

Drug consists of root, 7-18 cm long and 0.3-0.7 cm in diameter, slender, cylindrical, fibrous, frequently branched bearing a number of small rootlets, tough, woody and yellow to light brown in colour, surface becomes rough due to presence of small nodules, fracture fibrous, odour aromatic, taste, sweetish and astringent.

b) Microscopic

Transverse section of primary roots show a layer of epidermis followed by 4-5 layers of thin-walled parenchymatous cortex, endodermis distinct, pericycle enclosing diarch stele, in mature root, cork 4-6 layered, cork cambium single layered followed by 6-14 layers of thin-walled parenchymatous cells with varying number of fibres, distributed throughout, some secondary cortex cells show secondary wall formation and reticulate thickening, fibres found in groups resembling those of phloem, secondary phloem divided into two zones, outer zone characterised by presence of numerous phloem fibres with a few sieve tubes slightly collapsed, inner zone frequently parenchymatous, devoid of fibres often showing sieve tubes and companion cells, phloem rays distinct, few cells get converted into fibres in outer region, cambium 3-5 layered, wood composed of vessels, tracheids , parenchyma and fibres and traversed by medullary rays, vessels scattered, arranged in singles or doubles towards inner side, in groups of three to four on outer side having bordered pits, tracheids long, narrow with simple pits, xylem parenchyma rectangular or slightly elongated with simple pits and reticulate thickening, xylem fibres few, trachieds elongated with simple pits, medullary rays heterogenous, 1-4 cells wide, starch grains and rosette crystals of calcium oxalate present in secondary cortex, phloem and medullary rays cells, few prismatic crystals also present in xylem ray cells.

IDENTITY, PURITY AND STRENGTH

Foreign matter Not more than 2 per cent, Appendix 2.2.2.
Total Ash Not more than 13 per cent, Appendix 2.2.3.
Acid-insoluble ash Not more than 3 per cent, Appendix 2.2.4.
Alcohol-soluble extractive Not less than 4 per cent, Appendix 2.2.6.
Water-soluble extractive Not less than 10 per cent, Appendix 2.2.7.

CONSTITUENTS – Alkaloids and saponins.

PROPERTIES AND ACTION

Rasa : Madhura
Guna : Guru, Snigdha
Virya : Sita
Vipaka : Madhura
Karma : Mutrala, Vrsya, Vatanut, Brmhana

IMPORTANT FORMULATIONS – Sahacaradi Taila, Dasamula Kvatha Curna, Dasam ulakautraya Kvatha Curna, Dasam ulapancakoladi Kvatha Curna

THERAPEUTIC USES – Svasa, Hrdroga, Kasa, Vataroga, Sularoga, Mutrakrcchra, Asamari

DOSE – 20-30 g of the drug for decoction.

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KANCANARA

Kancanara consists of the dried, stem bark of Bauhinia variegata Blume (Fam. Leguminosm): a medium sized tree occurring in sub-Himalayan tract extending eastwards to Assam, Eastern, Central and South India.

SYNONYMS

Sanskrit : Kancanaraka
Assamese : Kancan, Kanchan
Bengali : Kanchana, Rakta Kanchana
English : Mountain Ebony
Gujrati : Champakati, Kanchnar, Kachnar
Hindi : Kachanar, Kanchanar, Kachnar
Kannada : Keyumandar, Kanchavala
Kashmiri : Kalad
Malayalam : Chuvanna Mandharam
Marathi : Kanchana, Raktakancana
Oriya : Kachana, Kaniara
Punjabi : Kanchnar
Tamil : Sigappu mandarai, Sihappu mantarai
Telugu : Deva Kanchanam
Urdu : —

DESCRIPTION

a) Macroscopic

Bark, dark brown, sometimes with silvery patches, rough, compact, exfoliating in woody strips and scales, outer surface with small transverse and longitudinal cracks, internal surface white, taste, astringent

b) Microscopic

Transverse section of mature stem bark shows a wide stratified cork, outer cork composed of thin-wailed, slightly compressed, yellow brown cells followed by a number of layers of brown coloured cells, inner cork composed of transversely elongated orange brown cells, cork interrupted at certain places due to formation of rhytidoma, some secondary cortex composed or 15 or more rows or transversely elongated to circular, thin-walled, parenchymatous cells, some secondary cortex cells contain orange brown contents: groups of stone cells found scattered in this region occasionally arranged in 1-7 or more tangential rows, pericyclic fibres, thick-walled with narrow lumen, scattered in secondary cortex in singles or in groups, secondary phloem consists of sieve tubes, companion cells, phloem parenchyma and fibres traversed by funnel shaped medullary rays , phloem fibres arranged in radial rows throughout phloem region, prismatic and rhomboidal crystals or calcium, oxalate abundantly found in phloem and secondary cortex regions, very rarely found in cork cells, cluster crystals also present in secondary cortex and secondary phloem, crystal fibres also found in secondary phloem. Powder – pinkish, under microscope showing abundant crystals of calcium oxalate, sc1ercids in singles or in groups with wide lumen, bits of fibres, cork and secondary cortex cells, containing coloured content, and numerous crystal fibres

IDENTITY, PURITY AND STRENGTH

Foreign matter Not more than 2 per cent, Appendix 2.2.2.
Total Ash Not more than 11 per cent, Appendix 2.2.3.
Acid-insoluble ash Not more than 0.2 per cent, Appendix 2.2.4.
Alcohol-soluble extractive Not less than 2 per cent, Appendix 2.2.6.
Water-soluble extractive Not less than 6 per cent, Appendix 2.2.7.

CONSTITUENTS – Tannins.

PROPERTIES AND ACTION

Rasa : Kasaya
Guna : Laghu, Ruksa
Virya : Sita
Vipaka : Katu
Karma : Dipana, Grahi, Tridosahara, Gandavrddhihara

IMPORTANT FORMULATIONS – Kancanaraguggulu

THERAPEUTIC USES – Apaci, Gandamala, Krmiroga, Vrana, Gudabhramsa

DOSE – 20-30 g of the drug for decoction.

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GAMBHARI

Gambhari consists of dried, mature root and root bark of Gmelina arborea Roxb. (Fam. Verbenaceae) , tree about 18 m high, with a clear bole of 6-9 m and a girth of 1.5-2.1 m, found in the lower Himalayas, the Nilgiris and the East and West Coasts of India.

SYNONYMS

Sanskrit : Kasmari, Kasmarya
Assamese : Gamari
Bengali : Gambhar, Gamar
English : Candhar Tree
Gujrati : Shivan
Hindi : Gambhar, Khambhari
Kannada : Shivanigida, Shivani
Kashmiri : Kashmari
Malayalam : Kumizhu, Kumpil
Marathi : Shivan
Oriya : Gambhari
Punjabi : Gumhar, Kumhar
Tamil : Kumishan, Kumizhan
Telugu : Peggummudu, Peggummadi
Urdu : —

DESCRIPTION

a) Macroscopic

Root – Occurs in pieces with secondary and tertiary branches, root pieces nearly cylindrical with uneven surface, greyish brown, fracture somewhat tough in bark, brittle and predominant in woody portion. Root bark-mature root bark when fresh, yellowish in colour, dry pieces curved and channelled, thinner ones forming single quills, external surface rugged due to presence of vertical cracks, ridges, fissures and numerous lenticels, fracture short and granular, taste, mucilaginous, sweetish with slight bitterness.

b) Microscopic

Root-transverse section of root shows 6-8 layers of cork cells, secondary cortex, including primary and secondary phloem about two third consisting of wood, cork brownish, cells arranged in tangential direction and broken at places towards upper layers, cortex characterised by the presence of thin-walled parenchymatous cells with starch grains , resin ducts present in abundance throughout cortex, scattered stone cells fibre like or elongated common, fibres present, occurring mostly in singles, cells of cortex also contain rosette crystals of calcium oxalate and oil globules, primary phloem characterised by the presence of sieve tubes with companion cells, phloem parenchyma, soft bast fibres and ray cells, phloem fibres occur singly and scattered cortical cells 40-70 n by 25-35 n and bast fibres, 300-1000 n by 10-15 n development of cork takes place in second or third layer of primary cortex, wood consists of simple pitted wood parenchyma and medullary rays, wood cells mainly composed of vessels and tracheids and inner wood consists of a major portion of fibres together with a few vessels, vessels numerous and form almost a ring near the periphery of xylem cylinder and somewhat spares, being scattered in groups or singly nearer the central region, lumen of vessels somewhat large, dimensions of vessels 130-250 n by 50-100 n and those of the tracheids 175-300 n by 30-50 n wood fibres abundant and with simple pits , cambium distinct, medullary rays generally 1-2 celled thick with abundant starch grains cells oblong to rectangular.

IDENTITY, PURITY AND STRENGTH

Foreign matter Not more than 2 per cent, Appendix 2.2.2.
Total Ash Not more than 5 per cent, Appendix 2.2.3.
Acid-insoluble ash Not more than 0.3 per cent, Appendix 2.2.4.
Alcohol-soluble extractive Not less than 7 per cent, Appendix 2.2.6.
Water-soluble extractive Not less than 20 per cent, Appendix 2.2.7.

CONSTITUENTS – Alkaloids and lignans (arboreal, isoarboreal and related lignans).

PROPERTIES AND ACTION

Rasa : Tikta, Kasaya
Guna : Guru
Virya : Usna
Vipaka : Katu
Karma : Sothahara, Bhedana, Dipana, Pacana, Tridosajit, Visaghna, Medhya, Jvarahara.

IMPORTANT FORMULATIONS – Dasamularisa, Dasamulaharitaki, Dasamula Ghrta, Dasamula Sapalaka Ghrta

THERAPEUTIC USES – Sotha, Daha, Jvara, Trsna, Arsa

DOSE – 20-30 g of the drug for decoction.

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KANKOLA

Kankola consists of mature, dried fruits of Piper cubeba Linn.f. (Fam. Piperacem), woody, climbing, perennial with dioeceous flowers in spike, cultivated to a small extent in India, specially in the Karnataka state, fruits collected when mature but still unripe and carefully dried.

SYNONYMS

Sanskrit : Kankolaka, Cinosana, Cinatiksna, Kakkola, Kankolika
Assamese : Kakkol, Kababcheni
Bengali : Kahabcbini, Sugandhamaricha
English : Cubebs, Tailed Pepper
Gujrati : Chanakabab, Chinikabab
Hindi : Seetalchini, Kababchini
Kannada : Gandhamenasu, Balamenasu
Kashmiri : Kushfal, Kababchini
Malayalam : Cheenamulaku, Takkolam, Valmulaku
Marathi : Kankol
Oriya : Kababchini
Punjabi : Kababchini, Sardchini
Tamil : Vaali milaku, Valmilagu
Telugu : Chalavamiriyalu, Tokamiriyalu
Urdu : Kababchini

DESCRIPTION

a) Macroscopic

Fruit wrinkled, rounded, 5-7 mm in diameter, light brown to dark brown, about 7 mm long stalk attached, pericarp red to slightly brown, testa fused with pericarp, fruit hard and stony albumen white and oily, odour, aromatic end characteristic, taste, pungent and slightly bitter.

b) Microscopic

Transverse section of fruit shows an outer layers of epidermis, externally covered with thick cuticle, a raw of 2-5 small, crushed, brown and thick-walled cells below, mesocarp composed of large, thin-walled parenchymatous cells, oil cells and vascular bundles, endocarp of multi-layered sclereids heavily lignified with narrow lumen, testa and tegmen composed of elongated cells tegmen cells hyaline and kernel cells greyish in colour.

IDENTITY, PURITY AND STRENGTH

Foreign matter Not more than 2 per cent, Appendix 2.2.2.
Total Ash Not more than 8 per cent, Appendix 2.2.3.
Acid-insoluble ash Not more than 1 per cent, Appendix 2.2.4.
Alcohol-soluble extractive Not less than 14 per cent, Appendix 2.2.6.
Water-soluble extractive Not less than 11 per cent, Appendix 2.2.7.

CONSTITUENTS – Essential oil (cubebin).

PROPERTIES AND ACTION

Rasa : Katu, Tikta
Guna : Laghu, Tiksna
Virya : Usna
Vipaka : Katu
Karma : Dipana, Kaphavatahara, Pacana, Rucya, Vastisodhana, Mukhadaurgandhyahara

IMPORTANT FORMULATIONS – Dasamularisa, Kumaryasava

THERAPEUTIC USES – Sula, Aruci, Mutrakrcchra, Mukharoga

DOSE – 1-2 g of the drug in powder form.

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ERANDA

Eranda consists of dried, mature roots of Ricinus communis Linn. (Fam. Euphorbiaceae), a tall glabrous shrub or almost small tree 2-4 m high, found throughout India, mostly growing wild on waste land and also cultivated for its oil seeds.

SYNONYMS

Sanskrit : Gandharvahasta, Vatari, Pancangula, Citra, Urubu, Rubu
Assamese : Eda, Era
Bengali : Bherenda
English : Castor oil plant
Gujrati : Erandio, Erando
Hindi : Arand, Erand, Andi, Rend
Kannada : Haralu, Oudala gida
Kashmiri : Aran, Banangir
Malayalam : Avanakku
Marathi : Erand
Oriya : Jada, Gaba
Punjabi : Arind
Tamil : Amanakku
Telugu : Amudapu veru
Urdu : Bedanjir, Arand

DESCRIPTION

a) Macroscopic

Root light in weight almost straight with few rootlets, outer surface dull yellowish brown, nearly smooth but marked with longitudinal wrinkles, some places whitish-yellow and soft, odourless, taste, acrid.

b) Microscopic

Transverse section of root shows thin layer of cork of squarish to tangentially elongated, thin-walled cells, beneath cork, secondary cortex of thin-walled, tangentially elongated cells, narrow cortex of rounded to tangentially elongated thin-walled parenchymatous cells, some containing large oil globules, rosettes of calcium oxalate crystals and round simple or compound starch grains, phloem a broad zone, consisting of sieve tubes, phloem parenchyma and phloem fibres, fibres long, mostly septate, highly thickened, having narrow lumen, some fibres surrounded by concentric rows of cells containing crystals of calcium oxalate, sieve tubes, thin-walled with companion cells and phloem parenchyma in the inner region of phloem more prominent , some phloem parenchyma cells contain crystals of calcium oxalate , cambium 3-5 layered, cells rectangular in shape, xylem occupies major part of root, pentarch, five groups of primary xylem distinct in the centre of the wood, xylem consists of vessels, parenchyma and fibres , vessels uniformly scattered throughout the xylem region, either solitary or in groups, larger in size towards phloem, with bordered pits , xylem parenchyma less ia number around vessels containing starch grains, xylem fibres long and thick-walled, medullary rays uni-to-biseriate, more or less straight, 4-5 seriate rays, sometimes found near protoxylem groups, ray cells, thin-walled, slightly radially elongated in phloem region, thick-walled in xylem region, all ray cells contain starch grains.

IDENTITY, PURITY AND STRENGTH

Foreign matter Not more than 2 per cent, Appendix 2.2.2.
Total Ash Not more than 8 per cent, Appendix 2.2.3.
Acid-insoluble ash Not more than 1 per cent, Appendix 2.2.4.
Alcohol-soluble extractive Not less than 3 per cent, Appendix 2.2.6.
Water-soluble extractive Not less than 9 per cent, Appendix 2.2.7.

CONSTITUENTS – Alkaloid (ricinine).

PROPERTIES AND ACTION

Rasa : Madhura
Guna : Guru, Snigdha
Virya : Usna
Vipaka : Madhura
Karma : Vatahara, Vrsya, Amapacana

IMPORTANT FORMULATIONS – Grandharvahastadi Kvatha Curna, Vatari Guggulu, Gandharvahasta taila

THERAPEUTIC USES – Sotha, Jvara, Udararoga, Amavata, Vastisula, Kaisula

DOSE – 20-30 g of the drug for decoction.

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KANTAKARI

Kanakari consists of mature, dried whole plant of Solanum surattense Burm. f., Syn. Solanum xanthocarpum Schrad . & Wendl , (Fam. Solanacem), perennial, very prickly diffused herb of waste land, found throughout India.

SYNONYMS

Sanskrit : Vyaghri, Nidigdhika, Ksudra, Kantakarika, Dhavani, Nidigdha, Dusparsa
Assamese : Katvmdana, Kantakar
Bengali : Kantakari
English : Febrifuge plant
Gujrati : Bharingani
Hindi : Katai, Katali, Ringani, Bhatakataiya, Chhotikateri
Kannada : Nelagulla, Kiragulla
Kashmiri : Kath
Malayalam : Kantakari chunda
Marathi : Bhauringani, Kataringani
Oriya : Bhejibaugana, Ankarati, Chakada Bhoji
Punjabi : Kandiari
Tamil : Kandangatri, Kandankatri, Kandanghathiri
Telugu : Nelamulaka, Pinnamulaka, Mulaka, Chinnamulaka, Vakudu
Urdu : —

DESCRIPTION

a) Macroscopic

Root-10-45 cm long, few mm to two cm in diameter, almost cylindrical and tapering, bearing a number of fine longitudinal and few transverse wrinkles with occasional scars or a few lenticels and small rootlets, transversely smoothened surface shows a thin bark and wide compact cylinder of wood, fracture, short, taste, bitter.

Stem-herbaceous, prickly with prominent nodes and internodes, green when fresh, young branches, covered with numerous hairs, mature ones glabrous, furrows more prominent in young stem appearing almost circular towards basal region, stem pieces 8-10 mm thick of variable length, external surface light green, when dry, surface yellowish green and smooth, transversely smoothened surface shows a very thin bark and prominent wood, centre shows a large and distinct, pith, mr ture and dry stem often with hollow pith, fracture short to slightly fibrous.

Leaves-petiolate, exstipulate, ovate–oblong or elliptic, sinuate or sub-pinnatifid, subacute hairy, 4-12.5 cm long and 2-7.5 cm wide, green, veins and midrib full with sharp prickles, odour and taste not distinct.

Flower– ebracteate, pedicellate, bisexual, pentamerous, regular, complete, bright blue or bluish purple, calyx-persistent, gamosepalous, tube short, globose, linear-lanceolate, acute, hairy, 0.5-1 .3 cm long and densely prickly, corollagamopetalous, lobes deltoid, acute, hairy, 1-2 cm long and purple in colour, stamens 5, epipetalous, basifixed, filament short 1-1.5 mm long, anther, oblong lanceolate, 0.7-0.8 cm long, ovary superior, ovoid, glabrous, bilocular with axile placentation having numerous ovules.

Fruit-Berry globular, measuring 0.8-1 cm in diameter, surrounded by persistent calyx at base unripe fruits variegated with green and white strips, ripe fruit shows different yellow and white shades.

Seeds-circular, flat, numerous, embedded in a fleshy mesocarp about 0. 2 cm in diameter, glabrous taste, bitter and acrid.

b) Microscopic

Root– transverse section of mature root shows cork composing of 3-6 layers of thinwalled, rectangular and tangentially elongated cells, cork cambium single layered followed by 6-15 layers of thin-walled, tangentially elongated to oval or circular parenchymatous cells, stone cells either single or in groups of 2-20 or even more present in this region, secondary phloem composed of sieve elements and phloem parenchyma traversed by medullary rays, stone cells present in singles or in groups of 2-20 or more in outer, and middle phloem regions, phloem rays 1-4 cells wide and 2-22 cells high, cambium 3-5 layered of thin-walled rectangular cells, xylem composed of vessels, tracheids, fibre trachieds, parenchyma and transversed by medullary rays, all elements being lignified, vessels and tracheids with bordered pits, fibres with a few simple pits, xylem parenchyama rectangular or lightly elongated with simple pits and rarely with reticulate thickening, xylem rays 1-3 cells wide and 1-20 cells high, microsphenoidal crystals of calcium oxalate as sandy masses and simple starch grains present in secondary cortex, phloem and medullary rays.

Stem-transverse section of mature stem, 1.5-2 cm thick consists of 6-12 layers of cork of thin- walled somewhat rectangular cells, epidermis remains intact for a long time, secondary cortex consists of 7-11 layers of parenchymatous cells, some cells thickened and lignified forming stone cells primary cortex remains intact even in quite mature stage but later gets crushed, pericyclic fibre, occur singly or in small groups of 2-3, secondary phloem consists of sieve elements, parenchyama, a few fibres, stone cells and traversed by phloem rays, fibres found scattered in singles or in small groups in outer and middle phloem region, inner phloem devoid of fibres, stone cells present in singles or in small groups of 2-4, phloem rays, 1-2 or rarely 3 cells wide, cambium composed of 2-3 layers, xylem consists of vessels, tracheids, parenchyma, fibres and traversed by xylem rays, vessels vary grea tly in shape and size and show bordered pits, tracheids elongated with irregular walls and bordered pits, fibres much elongated, thick-walled and lignified with tapering and pointed ends, some having truncated ends or bifurcated at one or both ends with a few simple pits, trancheids fibres smaller than fibres, with both ends tapering and have reticulate thickening, xylem parenchyma cubical to rectangular with simple or bordered pits or reticulate thickening, xylem rays conspicuous by their pitted thickenings, longer size and radial elongation of cells, 1-2 or rarely 3 cells wide and 2-25 cells high, internal phloem composed of sieve elements and parenchyma, forming more or less continuous band and embedded in perimedullary zone, a few phloem fibres similar to those of outer phloem region also present, central region occupied by a large pith, microsphenoidal crystals of calcium oxalate as sandy masses and simple starch grains present in cortex, secondary cortex, phloem, medullary rays and pith cells.

Leaves-Petiole-transverse section of petiole shows circular to wavy outlines, epidermis single layered, covered externally by a thick cuticle, hypodermis consists of 3-4 layers of
collenchymatous, cells, one large-crescent-shaped, bicollateral, central vascular bundle and two small lateral bundles present, rest of tissue of petiole composed of polygonal, angular, thin-walled, parenchymatous cells, epidermis shows mostly stellate and rarely urn to tricellular hairs.

Midrib-transverse section of midrib shows a biconvex structure, epidermis on either side covered externally by a thick cuticle, below epidermis 3-4 layers of collenchyma present, stele composed of crescent-shaped, bicollateral, central vacscular bundle and two small lateral vascular bundles, rest of tissue composed of thin-walled, parenchyma, some stellate hair present on epidermis.

Lamina-transverse section shows dorsiventral structure, epidermis on either side, wavy in outline, covered externally by a thick cuticle, on upper side mesophyll composed of a single layered palisade and 4-6 layers of loosely arranged spongy parenchyma, some stellate hairs (4-8 armed) present on both sides of epidermis, anisocytic stomata present on both surfaces, vein-islet number 46-80 on lower epidermis (mean 63), 61-80 on upper epidermis (mean 70), stomatal index 20-25 (mean 22.5) on lower epidermis, 14-24 (mean 19) on upper epidermis, palisade ratio 1.7-4 (mean 2 .85).

Fruit-transverse section of mature fruit shows single layered epidermis, covered externally by a thin cuticle, 1-2 layers of collanchyma present below epidermis, mesocarp composed of thin-walled, oval to polygonal cells, some fibre., vascular bundles present scattered, seed consists of thick-walled radially elongated testa, narrow endosperm with embryo, some cells of endosperm contain oil globules.

Powder – Greenish, under microscope shows single or groups of stone cells, groups of aseptate fibre with tapering ends, pitted vessels, groups of spongy parenchyma, fragments of palisade tissue, anisocytic stomata, stellate hairs and simple, rounded to oval starch grains measuring 2.75-11 n in dia.

IDENTITY, PURITY AND STRENGTH

Foreign matter Not more than 2 per cent, Appendix 2.2.2.
Total Ash Not more than 9 per cent, Appendix 2.2.3.
Acid-insoluble ash Not more than 3 per cent, Appendix 2.2.4.
Alcohol-soluble extractive Not less than 6 per cent, Appendix 2.2.6.
Water-soluble extractive Not less than 16 per cent, Appendix 2.2.7.

CONSTITUENTS – Glucoalkaloids and sterols.

PROPERTIES AND ACTION

Rasa : Katu, Tikta
Guna : Laghu, Ruksa
Virya : Usna
Vipaka : Katu
Karma : Sothahara, Dipana, Pacana, Amadosanasaka, Kanthya

IMPORTANT FORMULATIONS – Kanakaryavaleha, Pancatiktaka Ghrta, Vyaghriharitaki

THERAPEUTIC USES – Aruci, Svasa, Jvara, Kasa, Pinasa, Svarabheda, Parsvasula

DOSE – 20-30 g of the drug for decoction.

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DHATAKI

Dhataki Dhataki consists of flowers of Woodfordia fruticosa (Linn.) Kurz. (Fam. Lythraceae) : much branched, semi deciduous, undershrub or shrub, 1-3 m high, rarely upto 3 m, found throughout India, ascending to 1500 m in Himalayas and also in the Gangetic plains , also cultivated in gardens.

SYNONYMS

Sanskrit : Bahupuspi, Tamrapuspi, Vahnijvala
Assamese : Dhaiphool
Bengali : Dhaiphul
English : Fire flame bush
Gujrati : Dhavadi, Dhavani
Hindi : Dhai, Dhava
Kannada : Dhataki, Tamrapushpi
Kashmiri : Kath
Malayalam : Tattiripuvu, Tatire
Marathi : Dhayati, Dhavati
Oriya : Dhaiphula, Dhatuki
Punjabi : Davi, Phul Dhava
Tamil : Kattati, Kattathi., Kattattipoo
Telugu : Aarl Puruvu
Urdu : —

DESCRIPTION

a) Macroscopic

Flower, about 1.2 cm long, occurs as single or in bunches of 2-15, calyx 1.0-1.6 cm long, ridged and glabrous, bright red when fresh but fades on drying, with campanulate base and oblique apex having 6 triangular and acute teeth, each tooth being, 2-2.5 mm long, 6, very minute accessory sepals attached outside at the juncture of calyx tooth and deeper in colour, petals 6, attached inside the mouth of calyx-tube, shightly longer than calyx tooth, alternating with calyx-tooth pale rose or whitish, thin, papery, lanceolate, acuminate, stamens 12, united at the base, about 1.5-2 cm long, filament filiform, curved at the apex, keeping anthers inside calyx-tube , anthers dorsifixed brown, almost rounded or broadly ovate, carpels 2, united, ovary superior, style filiform, longe, than ovary and stamens, taste, astringent.

b) Microscopic

Transverse section of sepal shows, single layered cuticularised epidermis, provided with both glandular and covering trichomes ;glandular trichomes, multicellular, long, consisting of a stalk and a globose, thin-walled, multicellular head, covering trichomes, unicellular thick-walled broad at base and pointed at the apex, ground tissue consisting of thin-walled, parenchymatous cells surface view of petal shows thin-walled, parenchymatous cells, provided with very few sparsely distributed covering trichomes, transverse section of filament shows, epidermis consisting of single layered tangentially elongated cells, covered with a very thick-cuticle, ground tissue consisting of thin walled parenchymatous cells with intercellular spaces, surrounding a central. vascular cylinder of spirally thickened vessels, transverse section of anther shows, single layered epidermis, covered with cuticle followed by several layers of thickened cells, surrounding both the pollen-sacs having numerous pollen grains, pollen grains roughly tetrahedral with three pores, measuring 12-16 n approximately , central region consisting of thin-walled cells emboding vascular bundles.

IDENTITY, PURITY AND STRENGTH

Foreign matter Not more than 2 per cent, Appendix 2.2.2.
Total Ash Not more than 10 per cent, Appendix 2.2.3.
Acid-insoluble ash Not more than 1 per cent, Appendix 2.2.4.
Alcohol-soluble extractive Not less than 7 per cent, Appendix 2.2.6.
Water-soluble extractive Not less than 28 per cent, Appendix 2.2.7.

CONSTITUENTS – Tannin and glucoside.

PROPERTIES AND ACTION

Rasa : Katu, Kasaya
Guna : Laghu
Virya : Sita
Vipaka : Katu
Karma : Grahi, Visaghna, Garbhasthapana, Krminut, Sandhaniya.

IMPORTANT FORMULATIONS – Brhat Gangadhara Curna

THERAPEUTIC USES – Atisara, Raktapitta, Trsna, Vrana, Visarpa

DOSE – 3-6 g. of drug in powder form.

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KANYASARA

Kanyasara consists of dried juice of leaves of Aloe barbadensis Mill. Syn. Aloe vera Tourn.ex Linn, Aloe indica Royle. (Fam. Liliacem), shrub planted in many Indian gardens and found growing throughout India.

SYNONYMS

Sanskrit : Kumarirasasambhava, Sahasara
Assamese : Musabhar, Machambar
Bengali : Ghritakalmi
English : Indian Aloe
Gujrati : Eliyo, Eariyo
Hindi : Musabhar, Elva
Kannada : Karibola, Lolesara satva, Lovalsara, Lolesara
Kashmiri : Musabbar, Siber
Malayalam : Chenninayakam
Marathi : Korphad
Oriya : Musabara
Punjabi : Kalasohaga, Mussabar, Alua
Tamil : Kattazhi, Satthukkathazhai
Telugu : Musambaram
Urdu : Musabbar, Ailiva, Siber

DESCRIPTION

a) Macroscopic

Dark chocolate brown, to black, compact, irregular masses: surface dull, opaque with slightly vitreous appearance, odour, characteristic, taste, nauseous and bitter.

b) Microscopic

Powder when mounted in glycerin or lactophenol and examined under the microscope shows innumerable crystalline, yellowish-brown to chocolate coloured particles of varying size and shape.

IDENTITY, PURITY AND STRENGTHIdentification:

Mix 0.5 g with 50 ml of water, boil until nearly dissolved, cool, add 0.5 g of Kieselguhr and filter, to the filtrate apply the following tests-

(i) Heat 5 ml of filtrate with 0.2 g of Borax until dissolved, add a few drops of this solution to a test-tube nearly filled with Water, a green fluorescence is produced.
(ii) Mix 2 ml of filtrate with 2 ml of a freshly prepared solution of Bromine, a pale yellow precipitate is produced.

IDENTITY, PURITY AND STRENGTH

Foreign matter Not more than 2 per cent, Appendix 2.2.2.
Total Ash Not more than 5 per cent, Appendix 2.2.3.
Acid-insoluble ash Not more than 2 per cent, Appendix 2.2.4.
Alcohol-soluble extractive Not less than 80 per cent, Appendix 2.2.6.
Water-soluble extractive Not less than 60 per cent, Appendix 2.2.7.
Moisture content Not more than 10 per cent, Per cent of its weight when dried to constant weight at 105o C 2.2.9

CONSTITUENTS – Anthraquinone, glycoside

PROPERTIES AND ACTION

Rasa : Katu
Guna : Usna
Virya : Usna
Vipaka : Katu
Karma : Bhedi, Pittanirharana, Rajahpravartaka, Jvaranut.

IMPORTANT FORMULATIONS – Rajahpravartini Vati, Cukkumtippalyadi Gutika

THERAPEUTIC USES – Jvara, Udararoga, Kastartava, Yakrdvikara

DOSE – 125 – 500 mg of the drug in powder form.

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KARANJA

Karanja consists of seeds of Pongamia pinnata (Linn.) Merr, Syn. Pongamia glabra vent.(Fam. Leguminosm),a medium sized glabrous tree with a short bole and spreading crown and found almost throughout India upto an altitude of 1200 m.

SYNONYMS

Sanskrit : Karanjaka, Naktamala, Naktahva, Ghrtakaranja
Assamese : Korach
Bengali : Nata Karanja, Dahara Karanja
English : Smooth leaved pongamia
Gujrati : Kanajo, Karanji
Hindi : Dithouri, Karuaini
Kannada : Honge, Hulagilu
Kashmiri : Kath
Malayalam : Avittal, Ungu, Unu, Pungu
Marathi : Karanja
Oriya : Karnja
Punjabi : Karanj
Tamil : Pungan, Pongana
Telugu : Lamiga, Kanuga
Urdu : Karanj

DESCRIPTION

a) Macroscopic

Seed usually one and rarely two, elliptic or reniform in shape, 1.7-2.0 cm long and 1.2-1.8 cm broad, wrinkled with reddish leathery testa, micropylar end of cotyledons slightly depressed while other side semi-circular in shape.

b) Microscopic

Transverse section of seed shows, testa composed of a layer of palisade like outer epidermis, filled with brown pigment, covered externally with a thick cuticle, a layer of large, thin walled, somewhat rectangular cells, 2-4 layers of thick-walled parenchyma cells, a few rows of cells with small inter-cellular spaces, 2-3 layers of thick-walled elongated cells, a few layers of spongy parenchyma having large inter-cellular spaces, a number of parenchyma cells containing brown pigment, cotyledons composed of outer layer of epidermis with cylindrical cells, externally covered with thin cuticle, epidermis followed by rectangular to polygonal cells of mesophyll, filled with globules, also present scattered in this region.

IDENTITY, PURITY AND STRENGTH

Foreign matter Not more than 1 per cent, Appendix 2.2.2.
Total Ash Not more than 3 per cent, Appendix 2.2.3.
Acid-insoluble ash Not more than 0.1 per cent, Appendix 2.2.4.
Alcohol-soluble extractive Not less than 23 per cent, Appendix 2.2.6.
Water-soluble extractive Not less than 13 per cent, Appendix 2.2.7.

CONSTITUENTS – Fixed oil, flavones and traces of essential oil.

PROPERTIES AND ACTION

Rasa : Katu, Tikta
Guna : Tiksna
Virya : Usna
Vipaka : Katu
Karma : Krmijit, Kushaghna, Kaphavataghna, Vranasodhana

IMPORTANT FORMULATIONS – Aragvadhadi Kvath Curna, Pathyadilepa

THERAPEUTIC USES – Vrana, Krmi, Kustha.

DOSE – 0.25 g of the drug in powder form.
5-10 g of the drug for decoction.

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KARAVIRA

Karavira consists of dried leaves of Nerium indicum Mill. Syn. Nerium odorum Soland (Fam.Apocynacem), a large evergreen woody shrub with milky Juice, found throughout the year in upper Gangetic plains, Himalayas, from Nepal to Kashmir upto 2000 m. Central and Southern India, also cultivated near temples and gardens.

SYNONYMS

Sanskrit : Hayamaraka, Harapriya, Asvamara.
Assamese : Karbira, Karavi, Karvir
Bengali : Karavi, Kalkephul
English : Indian Oleander
Gujrati : Kanera, Karena, Karen
Hindi : Kaner
Kannada : Kanagalu, Kanagile
Kashmiri : Gandeela, Gandula
Malayalam : Kanave eram, Arali, Kattalari
Marathi : Kanher
Oriya : Kaniara, Kaniar
Punjabi : Kaner
Tamil : Arali, Alari, Aatrulari
Telugu : Ganneru
Urdu : Kaner

DESCRIPTION

a) Macroscopic

Leaves exstipulate, linear, lanceolate, 10-20 cm long and upto 2.5 cm wide, thick, dark green and shining above and dotted beneath, venation unicostate, reticulate with midrib being stout and the secondary veins arising in very large number, running parallel, stomata anamocytic.

b) Microscopic

Petiole-transverse section of petiole shows a single layer of epidermis covered externally by thick cuticle, epidermal cells elongate to form unicellular, non-lignified and nonglandular hairs, a wide zone of cortex, composed of 4-7 layers of collenchymatous cells and a Wide zone of parenchyma follows the epidermis, parenchymatous cells thinwalled,
more or less isodiametric with intercellular spaces, some cells contain rosette crystals of calcium oxalate, petiole receives three vascular bundles from stem, central one large and crescent shaped while other two much smaller and somewhat circular present on each side of central vascular bundle, phloem present on upper side and xylem on lower Side With usual elements.

Lamina-transverse section of lamina shows an isobilateral structure, upper epidermis composed of penta or hexagonal parenchymatous cells, externally covered with thick cuticle, below upper epidermis. 2-3 layers of hypodermis present, palisada 3-4 layered composed of elongated and compactly arranged cells, vascular strands also seen in between palisade and spongy parenchyma, spongy parenchyma filled with chlorophyll, towards lower surface 2-3 layered palisade, below which parenchyma and lower epidermis present, lower epidermis also coated with the cuticle externally, in lower surface many pits possessing stomata, unicellular, non-glandular and non-lignified trichomes, rosette crystals of calcium oxalate present throughout lamina, average palisade ratio 4: 1.

Midrib-transverse section of midrib shows epidermis composed of a layer of cells, externally covered with cuticle, some epidermal cells on upper and lower sides form unicellular hairs, between epidermis and parenchyma 2-4 rows of thick-walled cells, more prominent towards lower side, some parenchymatous cells contain rosette crystals of calcium oxalate, laticifers found scattered singly or in groups of 2 in this region, beneath the vascular bundle a sn ip of fibres present, vascular bundle ‘U’ shaped, xylem being towards lower side and phloem towards the upper consists of tracheids, vessels and parenchyma, vessels with end-openings, rarely with side openings tracheids many with spiral, annular or reticulate thickenings on their walls.

IDENTITY, PURITY AND STRENGTH

Foreign matter Not more than 12 per cent, Appendix 2.2.2.
Total Ash Not more than 9 per cent, Appendix 2.2.3.
Acid-insoluble ash Not more than 1 per cent, Appendix 2.2.4.
Alcohol-soluble extractive Not less than 20 per cent, Appendix 2.2.6.
Water-soluble extractive Not less than 20 per cent, Appendix 2.2.7.

CONSTITUENTS – Cardiac glucoside (oleandrin).

PROPERTIES AND ACTION

Rasa : Katu, Tikta, Kasaya
Guna : Laghu, Ruksa, Tiksna
Virya : Usna
Vipaka : Katu
Karma : Svasahara, Caksusya, Krmighna, Kandughna, Kushaghna, Vranapaha, Jvarapaha

IMPORTANT FORMULATIONS – Kasisadi Taila

THERAPEUTIC USES – Hrdroga, Jvara, Krmiroga, Kandu, Kustha, Netraroga, Vrana,Tamakasvasa

DOSE – 30-125 mg of the drug in powder form.
*Dose should not exceed the higher limit.

NOTE-Sodhana of this drug is to be done before use as described in the appendix.

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BILVA

Bilva consists of pulp of entire, unripe or half ripe fruits of Aegle marmelos Carr. (Fam. Rutaceae), a tree, attaining a height of 12 m growing wild and also cultivated throughout the country, rind of fruit is removed and pulp is bruised and dried.

SYNONYMS

Sanskrit : Sriphala
Assamese : Bael, Vael
Bengali : Bela, Bilva
English : Bengal Quince, Bael fruit
Gujrati : Bill, Bilum, Bilvaphal
Hindi : Bela, Sriphal, Bel
Kannada : Bilva
Kashmiri : Bel
Malayalam : Koovalam
Marathi : Bel, Baela
Oriya : Bela
Punjabi : Bil
Tamil : Vilvam
Telugu : Maredu
Urdu : Bel

DESCRIPTION

a) Macroscopic

Fruit, sub-globose, 5-18 cm in diameter, externally greenish when young, yellowish-brown when ripe, rind about 1.5 mm-3 mm thick, hard and woody, surface smooth or slightly granular bearing a circular scar at the point of attachment with peduncle, carpels, 10-15, central, each containing several hairy seeds embedded in yellowishbrown, extremely sticky mucilage, seeds oblong, flat, woody, and having white hair, fresh pulp of ripe fruit, brown, of sticky shreads, dried pulp hard and pale to dark red in colour, frequently breaks away from the rind during drying, leaving a thin layer attached to it, odour, faintly aromatic, taste, mucilaginous and slightly astringent.

IDENTITY, PURITY AND STRENGTH

Total Ash Not more than 4 per cent, Appendix 2.2.3.
Acid-insoluble ash Not more than 1 per cent, Appendix 2.2.4.
Alcohol-soluble extractive Not less than 6 per cent, Appendix 2.2.6.
Water-soluble extractive Not less than 50 per cent, Appendix 2.2.7.

CONSTITUENTS – Marmalosin, tannins, mucilage, fatty oil and sugar.

PROPERTIES AND ACTION

Rasa : Katu, Tikta, Kasaya
Guna : Laghu, Ruksa
Virya : Usna
Vipaka : Katu
Karma : Balya, Dipana, Grahi, Pacana, Pittakrt, Vatakaphahara

IMPORTANT FORMULATIONS – Bilvadi Leha, Brhatgangadhara Curna

THERAPEUTIC USES – Pravahika, Agnimandya, Grahaniroga

DOSE – 3-6 g of the drug in powder form.

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AJAMODA

Ajamoda consists of dried, aromatic fruits of Apium leptophyllum (Pers.) F. V. M. ex Benth. (Fam. Umbelliferae); an annual herb cultivated in Andhra Pradesh, Gujarat, Madhya Pradesh and Karnataka; collected by thrashing plants on a mat and dried in shade or in drying sheds.

SYNONYMS

Sanskrit : Dipyaka
Assamese : Bonjamani, Bonajain, Yamani, Ajowan
Bengali : Randhuni, Banyamani
English : —
Gujrati : Bodi Ajamo, Ajamo
Hindi : Ajmuda, Ajmod
Kannada : Oma, Ajavana, Omakki
Kashmiri : Fakhazur, Banjuan
Malayalam : Ayamodakum, Omam
Marathi : Ajmoda, Oova
Oriya : Banajuani
Punjabi : Valjawain, Ajmod
Tamil : Omam
Telugu : Naranji vamu
Urdu : Ajmod

DESCRIPTION

a) Macroscopic

Drug consists of small, ovoid fruit; bulk colour yellowish brown, mainly occur as entire cremocarps with pedicel attached or detached and bifid stylopod, free ends curved sometimes occurs as separate mericarps; cremocarps glabrous, ovoid to conical, about 1.5-3.0 mm long and 1.2-2.8 mm wide, yellow to yellowish green; separated mericarps broadly ovoid, more or less curved, dorsal surface convex with five equally distinct, longitudinal primary ridges; at the summit curved stylopodiurn, commissural surface flat, showing darker and light coloured longitudinal bands, former representing the position of vittae and vascular bundles ; odour; aromatic; taste, slightly bitter giving a sensation of warmth to tongue.

b) Microscopic

Transverse section of fruit shows mericarps with four large vittae on dorsal surface, two on commissural surface and four primary ridges on dorsal surface; 3-5 secondary oil canals present under each primary ridge and also between ridges; carpophore present on commissural surface; epicarp cells with thin striated cuticle, outer walls drawn into papillae; stomata, anomocytic type upto 35 μ in diameter; mesocarp consists of polygonal paranchyma,: with thickened and lignified cells, measuring 30-62-95μ. in diameter with oval to round pits; collateral vascular bundles lie beneath epicarp; tracheids 25-203-388 μ in length with spiral, scalariform or reticulate thickenings; xylem parenchyma lignified, elongated with elliptical pits, measuring 52-118-176 by 13-30-44 μ large secondary vittac towards endosperm measure upto 123μ in width and towards periphery the smallest vittae measuring 184μ in diameter.

Powder-Shows moderately thick-walled cell of epicarp exhibiting characteristic striations and occasional presence of stoma, fragments of trichomes and glandular hairs, reticulate parenchymatous cells of mesocarp, fragments of yellowish-brown vittae; fragments of endosperm thick-walled polygonal cells containing aleurone grain and micro rosette crystals of calcium oxalate.

IDENTITY, PURITY AND STRENGTH

Foreign matter (Including fStalk) Not more than 5 per cent, Appendix 2.2.2.
Total Ash Not more than 14 per cent, Appendix 2.2.3.
Acid-insoluble ash Not more than 14 per cent, Appendix 2.2.4.
Alcohol-soluble extractive Not less than 14 per cent, Appendix 2.2.6.
Water-soluble extractive Not less than 3 per cent, Appendix 2.2.7.
Volatile oil Not less than 2 per cent v/w, Appendix 2.2.10

CONSTITUENTS – Essential oil and fixed oil.

PROPERTIES AND ACTION

Rasa : Katu, Tikta
Guna : Laghu, Ruksa
Virya : Usna
Vipaka : Katu
Karma : Dipana, Vidahi, Kaphavatajit, Rucikrt, Krmijit, Sulaghna

IMPORTANT FORMULATIONS – Ajamodarka, Ajamodadi Curna.

THERAPEUTIC USES – Gulma, Aruci, Adhmana, Hikka, Chardi Krmi Roga, Sula

DOSE – 1-3 g of the drug in powder form.

Note: Trachyspermum roxburghianum (DC) Sprague Syn. Carum roxburghianum Benth. Hook.f. is the common market substitute.

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BIBHITAKA

Bibhitaka consists of pericarp of dried ripe fruits of Terntinalia belerica Roxb. (Fam. Combretaceae), a large deciduous tree, 10-12 m or more high, commonly found in plain and forests upto 900 m elevation, fruits ripen towards November.

SYNONYMS

Sanskrit : Vibhita, Aksa, Aksaka
Assamese : Bhomora, Bhomra, Bhaira
Bengali : Bayada, Baheda
English : Beleric Myrobalan
Gujrati : Bahedan
Hindi : Bahera
Kannada : Tare kai, Shanti Kayi
Kashmiri : Babelo, Balali
Malayalam : Tannikka
Marathi : Baheda
Oriya : Baheda
Punjabi : Bahera
Tamil : Thanrikkai
Telugu : Thanikkaya
Urdu : Bahera

DESCRIPTION

a) Macroscopic

Fruit nearly spherical to ovoid, 2.5-4.0 cm in diameter, fresh ripe fruits slightly silvery or with whitish shiny pubescent surface, mature fruits grey or grayish brown with slightly wrinkled appearance, rind of fruit shows variation in thickness from 3-5 mm, taste, astringent.

b) Microscopic

Transverse section of fruit shows an outer epicarp consisting of a layer of epidermis, most of epidermal cells elongate to form hair like protuberance with swollen base, composed of a zone of parenchymatous cells, slightly tangentially elongated and irregularly arranged, intermingled with stone cells of varying shape and size, elongated stone cells found towards periphery and spherical in the inner zone of mesocarp in groups of 3-10, mesocarp traversed in various directions by numerous vascular strands, bundles collateral, endarch, simple starch grains and some stone cells found in most of mesocarp cells, few peripheral layers devoid of starch grains, rosettes of calcium oxalate and stone cells present in parenchymatous cells, endosperm composed of stone cells running longitudinally as well as transversely.

IDENTITY, PURITY AND STRENGTH

Foreign matter Not more than 2 per cent, Appendix 2.2.2.
Total Ash Not more than 7 per cent, Appendix 2.2.3.
Acid-insoluble ash Not more than 1 per cent, Appendix 2.2.4.
Alcohol-soluble extractive Not less than 8 per cent, Appendix 2.2.6.
Water-soluble extractive Not less than 35 per cent, Appendix 2.2.7.

CONSTITUENTS – Gallic acid, tannic acid and glycosides.

PROPERTIES AND ACTION

Rasa : Kasaya
Guna : Laghu, Ruksa
Virya : Usna
Vipaka : Madhura
Karma : Caksusya, Kesya, Kaphapittajit, Bhedaka, Krminasana, Kasahara

IMPORTANT FORMULATIONS – Triphala Curna, Triphaladi Taila, Lavanagadi Vati

THERAPEUTIC USES – Chardi, Kasa, Krmiroga, Vibandha, Svarabheda, Netraroga

DOSE – 3-6 g of the drug in powder from.

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